Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomi...
Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial
About this item
Full title
Author / Creator
Novak, Petr, Dr , Schmidt, Reinhold, Prof , Kontsekova, Eva, Prof , Zilka, Norbert, PhD , Kovacech, Branislav, PhD , Skrabana, Rostislav, PhD , Vince-Kazmerova, Zuzana, PhD , Katina, Stanislav, PhD , Fialova, Lubica, PhD , Prcina, Michal, PhD , Parrak, Vojtech, MD , Dal-Bianco, Peter, MD , Brunner, Martin, MD , Staffen, Wolfgang, MD , Rainer, Michael, MD , Ondrus, Matej, MD , Ropele, Stefan, Ing , Smisek, Miroslav, MD , Sivak, Roman, Ing , Winblad, Bengt, Prof and Novak, Michal, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
Formats
Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background Neurofibrillary pathology composed of tau protein is a main correlate of cognitive impairment in patients with Alzheimer's disease. Immunotherapy targeting pathological tau proteins is therefore a promising strategy for disease-modifying treatment of Alzheimer's disease. We have developed an active vaccine, AADvac1, against patho...
Alternative Titles
Full title
Safety and immunogenicity of the tau vaccine AADvac1 in patients with Alzheimer's disease: a randomised, double-blind, placebo-controlled, phase 1 trial
Authors, Artists and Contributors
Author / Creator
Schmidt, Reinhold, Prof
Kontsekova, Eva, Prof
Zilka, Norbert, PhD
Kovacech, Branislav, PhD
Skrabana, Rostislav, PhD
Vince-Kazmerova, Zuzana, PhD
Katina, Stanislav, PhD
Fialova, Lubica, PhD
Prcina, Michal, PhD
Parrak, Vojtech, MD
Dal-Bianco, Peter, MD
Brunner, Martin, MD
Staffen, Wolfgang, MD
Rainer, Michael, MD
Ondrus, Matej, MD
Ropele, Stefan, Ing
Smisek, Miroslav, MD
Sivak, Roman, Ing
Winblad, Bengt, Prof
Novak, Michal, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_500469
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_500469
Other Identifiers
ISSN
1474-4422
E-ISSN
1474-4465
DOI
10.1016/S1474-4422(16)30331-3
