Genetic modifiers of CHEK21100delC-associated breast cancer risk
Genetic modifiers of CHEK21100delC-associated breast cancer risk
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Author / Creator
Muranen, Taru A. , Greco, Dario , Blomqvist, Carl , Aittomäki, Kristiina , Khan, Sofia , Hogervorst, Frans , Verhoef, Senno , Pharoah, Paul D.P. , Dunning, Alison M. , Shah, Mitul , Luben, Robert , Bojesen, Stig E. , Nordestgaard, Børge G. , Schoemaker, Minouk , Swerdlow, Anthony , García-Closas, Montserrat , Figueroa, Jonine , Dörk, Thilo , Bogdanova, Natalia V. , Hall, Per , Li, Jingmei , Khusnutdinova, Elza , Bermisheva, Marina , Kristensen, Vessela , Borresen-Dale, Anne-Lise , Investigators, NBCS , Peto, Julian , dos Santos Silva, Isabel , Couch, Fergus J. , Olson, Janet E. , Hillemans, Peter , Park-Simon, Tjoung-Won , Brauch, Hiltrud , Hamann, Ute , Burwinkel, Barbara , Marme, Frederik , Meindl, Alfons , Schmutzler, Rita K. , Cox, Angela , Cross, Simon S. , Sawyer, Elinor J. , Tomlinson, Ian , Lambrechts, Diether , Moisse, Matthieu , Lindblom, Annika , Margolin, Sara , Hollestelle, Antoinette , Martens, John W.M. , Fasching, Peter A. , Beckmann, Matthias W. , Andrulis, Irene L. , Knight, Julia A. , Investigators, kConFab/AOCS , Anton-Culver, Hoda , Ziogas, Argyrios , Giles, Graham G. , Milne, Roger L. , Brenner, Hermann , Arndt, Volker , Mannermaa, Arto , Kosma, Veli-Matti , Chang-Claude, Jenny , Rudolph, Anja , Devilee, Peter , Seynaeve, Caroline , Hopper, John L. , Southey, Melissa C. , John, Esther M. , Whittemore, Alice S. , Bolla, Manjeet K. , Wang, Qin , Michailidou, Kyriaki , Dennis, Joe , Easton, Douglas F. , Schmidt, Marjanka K. , Nevanlinna, Heli , kConFab/AOCS Investigators and NBCS Investigators
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Purpose:
CHEK2
*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with
CHEK2
*1100delC is modified by other genetic factors in a multiplicative fashion. We have investigated this empirically...
Alternative Titles
Full title
Genetic modifiers of CHEK21100delC-associated breast cancer risk
Authors, Artists and Contributors
Author / Creator
Greco, Dario
Blomqvist, Carl
Aittomäki, Kristiina
Khan, Sofia
Hogervorst, Frans
Verhoef, Senno
Pharoah, Paul D.P.
Dunning, Alison M.
Shah, Mitul
Luben, Robert
Bojesen, Stig E.
Nordestgaard, Børge G.
Schoemaker, Minouk
Swerdlow, Anthony
García-Closas, Montserrat
Figueroa, Jonine
Dörk, Thilo
Bogdanova, Natalia V.
Hall, Per
Li, Jingmei
Khusnutdinova, Elza
Bermisheva, Marina
Kristensen, Vessela
Borresen-Dale, Anne-Lise
Investigators, NBCS
Peto, Julian
dos Santos Silva, Isabel
Couch, Fergus J.
Olson, Janet E.
Hillemans, Peter
Park-Simon, Tjoung-Won
Brauch, Hiltrud
Hamann, Ute
Burwinkel, Barbara
Marme, Frederik
Meindl, Alfons
Schmutzler, Rita K.
Cox, Angela
Cross, Simon S.
Sawyer, Elinor J.
Tomlinson, Ian
Lambrechts, Diether
Moisse, Matthieu
Lindblom, Annika
Margolin, Sara
Hollestelle, Antoinette
Martens, John W.M.
Fasching, Peter A.
Beckmann, Matthias W.
Andrulis, Irene L.
Knight, Julia A.
Investigators, kConFab/AOCS
Anton-Culver, Hoda
Ziogas, Argyrios
Giles, Graham G.
Milne, Roger L.
Brenner, Hermann
Arndt, Volker
Mannermaa, Arto
Kosma, Veli-Matti
Chang-Claude, Jenny
Rudolph, Anja
Devilee, Peter
Seynaeve, Caroline
Hopper, John L.
Southey, Melissa C.
John, Esther M.
Whittemore, Alice S.
Bolla, Manjeet K.
Wang, Qin
Michailidou, Kyriaki
Dennis, Joe
Easton, Douglas F.
Schmidt, Marjanka K.
Nevanlinna, Heli
kConFab/AOCS Investigators
NBCS Investigators
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_501944
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_501944
Other Identifiers
ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/gim.2016.147
