Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (...
Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
About this item
Full title
Author / Creator
O'Brien, Susan, Prof , Jones, Jeffrey A, MD , Coutre, Steven E, Prof , Mato, Anthony R, MD , Hillmen, Peter, Prof , Tam, Constantine, MD , Österborg, Anders, Prof , Siddiqi, Tanya, MD , Thirman, Michael J, MD , Furman, Richard R, MD , Ilhan, Osman, Prof , Keating, Michael J, Prof , Call, Timothy G, MD , Brown, Jennifer R, MD , Stevens-Brogan, Michelle, MSc , Li, Yunfeng, PhD , Clow, Fong, ScD , James, Danelle F, MD , Chu, Alvina D, MD , Hallek, Michael, Prof and Stilgenbauer, Stephan, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
Summary Background The TP53 gene, encoding tumour suppressor protein p53, is located on the short arm of chromosome 17 (17p). Patients with 17p deletion (del17p) chronic lymphocytic leukaemia have poor responses and survival after chemoimmunotherapy. We assessed the activity and safety of ibrutinib, an oral covalent inhibitor of Bruton's tyrosine k...
Alternative Titles
Full title
Ibrutinib for patients with relapsed or refractory chronic lymphocytic leukaemia with 17p deletion (RESONATE-17): a phase 2, open-label, multicentre study
Authors, Artists and Contributors
Author / Creator
Jones, Jeffrey A, MD
Coutre, Steven E, Prof
Mato, Anthony R, MD
Hillmen, Peter, Prof
Tam, Constantine, MD
Österborg, Anders, Prof
Siddiqi, Tanya, MD
Thirman, Michael J, MD
Furman, Richard R, MD
Ilhan, Osman, Prof
Keating, Michael J, Prof
Call, Timothy G, MD
Brown, Jennifer R, MD
Stevens-Brogan, Michelle, MSc
Li, Yunfeng, PhD
Clow, Fong, ScD
James, Danelle F, MD
Chu, Alvina D, MD
Hallek, Michael, Prof
Stilgenbauer, Stephan, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_502366
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_502366
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(16)30212-1