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Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmo...

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_507485

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis

About this item

Full title

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis

Publisher

England: BioMed Central Ltd

Journal title

Respiratory research, 2016-02, Vol.17 (1), p.14, Article 14

Language

English

Formats

Publication information

Publisher

England: BioMed Central Ltd

More information

Scope and Contents

Contents

Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease with a poor prognosis. Fibroblasts and myofibroblasts are the key cells in the fibrotic process. Recently two drugs, pirfenidone and nintedanib, were approved for clinical use as they are able to slow down the disease progression. The mechanisms by which these two drugs act in in vitr...

Alternative Titles

Full title

Pirfenidone and nintedanib modulate properties of fibroblasts and myofibroblasts in idiopathic pulmonary fibrosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_507485

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_507485

Other Identifiers

ISSN

1465-993X,1465-9921

E-ISSN

1465-993X,1465-9921

DOI

10.1186/s12931-016-0328-5

How to access this item