Structural insights into the DNA-binding specificity of E2F family transcription factors
Structural insights into the DNA-binding specificity of E2F family transcription factors
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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The mammalian cell cycle is controlled by the E2F family of transcription factors. Typical E2Fs bind to DNA as heterodimers with the related dimerization partner (DP) proteins, whereas the atypical E2Fs, E2F7 and E2F8 contain two DNA-binding domains (DBDs) and act as repressors. To understand the mechanism of repression, we have resolved the struct...
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Structural insights into the DNA-binding specificity of E2F family transcription factors
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TN_cdi_swepub_primary_oai_swepub_ki_se_508893
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_508893
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms10050
