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HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_511603

HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

About this item

Full title

HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

Publisher

Athens: D.A. Spandidos

Journal title

International journal of oncology, 2015-10, Vol.47 (4), p.1311-1320

Language

English

Formats

Publication information

Publisher

Athens: D.A. Spandidos

More information

Scope and Contents

Contents

The human epidermal growth factor receptor (HER) 4 is a relative of HER2 and has been associated to endocrine breast cancer and prediction of tamoxifen response. In addition to PI3K/Akt and MAPK pathway activation, ligand binding to HER4 triggers proteolytic cleavage and release of an intracellular receptor domain (4ICD) with signaling properties....

Alternative Titles

Full title

HER4 tumor expression in breast cancer patients randomized to treatment with or without tamoxifen

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_511603

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_511603

Other Identifiers

ISSN

1019-6439,1791-2423

E-ISSN

1791-2423

DOI

10.3892/ijo.2015.3108