Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes
Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes
About this item
Full title
Author / Creator
Åvall, Karin , Ali, Yusuf , Leibiger, Ingo B. , Leibiger, Barbara , Moede, Tilo , Paschen, Meike , Dicker, Andrea , Daré, Elisabetta , Köhler, Martin , Ilegems, Erwin , Abdulreda, Midhat H. , Graham, Mark , Crooke, Rosanne M. , Tay, Vanessa S. Y. , Refai, Essam , Nilsson, Stefan K. , Jacob, Stefan , Selander, Lars , Berggren, Per-Olof and Juntti-Berggren, Lisa
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Insulin resistance and β-cell failure are the major defects in type 2 diabetes mellitus. However, the molecular mechanisms linking these two defects remain unknown. Elevated levels of apolipoprotein CIII (apoCIII) are associated not only with insulin resistance but also with cardiovascular disorders and inflammation. We now demonstrate that local a...
Alternative Titles
Full title
Apolipoprotein CIII links islet insulin resistance to β-cell failure in diabetes
Authors, Artists and Contributors
Author / Creator
Ali, Yusuf
Leibiger, Ingo B.
Leibiger, Barbara
Moede, Tilo
Paschen, Meike
Dicker, Andrea
Daré, Elisabetta
Köhler, Martin
Ilegems, Erwin
Abdulreda, Midhat H.
Graham, Mark
Crooke, Rosanne M.
Tay, Vanessa S. Y.
Refai, Essam
Nilsson, Stefan K.
Jacob, Stefan
Selander, Lars
Berggren, Per-Olof
Juntti-Berggren, Lisa
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_513751
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_513751
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1423849112
