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The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_514892

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

About this item

Full title

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

Publisher

London: Nature Publishing Group UK

Journal title

Nature communications, 2015-03, Vol.6 (1), p.6340-6340, Article 6340

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Inflammation is closely related to the extent of damage following cerebral ischaemia, and the targeting of this inflammation has emerged as a promising therapeutic strategy. Here, we present that hypoxia-induced glial T-cell immunoglobulin and mucin domain protein (TIM)-3 can function as a modulator that links inflammation and subsequent brain dama...

Alternative Titles

Full title

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_514892

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_514892

Other Identifiers

ISSN

2041-1723

E-ISSN

2041-1723

DOI

10.1038/ncomms7340

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