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Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_515000

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

About this item

Full title

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

Publisher

New York: Nature Publishing Group US

Journal title

Nature medicine, 2015-04, Vol.21 (4), p.363-372

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

NMDA receptors in pancreatic beta cells inhibit glucose-stimulated insulin secretion, and inhibiting these receptors with an over-the-counter medication improves diabetes in mouse models
In the nervous system, NMDA receptors (NMDARs) participate in neurotransmission and modulate the viability of neurons. In contrast, little is known about the ro...

Alternative Titles

Full title

Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_515000

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_515000

Other Identifiers

ISSN

1078-8956

E-ISSN

1546-170X

DOI

10.1038/nm.3822

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