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A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_518342

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

About this item

Full title

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

Publisher

United States: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2014-10, Vol.346 (6206), p.237-241

Language

English

Formats

Publication information

Publisher

United States: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Neurogenesis is restricted in the adult mammalian brain; most neurons are neither exchanged during normal life nor replaced in pathological situations. We report that stroke elicits a latent neurogenic program in striatal astrocytes in mice. Notch1 signaling is reduced in astrocytes after stroke, and attenuated Notch1 signaling is necessary for neu...

Alternative Titles

Full title

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_518342

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_518342

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.346.6206.237

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