Maternally transmitted mitochondrial DNA mutations can reduce lifespan
Maternally transmitted mitochondrial DNA mutations can reduce lifespan
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
We recently showed that germline transmission of mitochondrial DNA mutations via the oocyte cause aggravation of aging phenotypes in prematurely aging mtDNA mutator (
PolgA
mut/mut
) mice. We discovered that 32% of these mice also exhibit stochastic disturbances of brain development, when maternal mtDNA mutations were combined with homozyg...
Alternative Titles
Full title
Maternally transmitted mitochondrial DNA mutations can reduce lifespan
Authors, Artists and Contributors
Author / Creator
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_518356
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_518356
Other Identifiers
ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/srep06569
