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Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence...

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_519508

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns

About this item

Full title

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns

Publisher

United States: National Academy of Sciences

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (35), p.E3735-E3744

Language

English

Formats

Publication information

Publisher

United States: National Academy of Sciences

More information

Scope and Contents

Contents

Significance Narcolepsy is a chronic sleep disease with autoimmune origin. We explored occurrence of autoantibodies in narcolepsy and other sleep-related disorders (OSRDs) by screening human sera with immunohistochemistry on rat brains. Hypocretin/orexinergic neurons were not stained, but a prominent immunostaining pattern of hypothalamic melanin-c...

Alternative Titles

Full title

Narcolepsy patients have antibodies that stain distinct cell populations in rat brain and influence sleep patterns

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_519508

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_519508

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.1412189111

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