Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in...
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Metabolic remodeling is now widely regarded as a hallmark of cancer, but it is not clear whether individual metabolic strategies are frequently exploited by many tumours. Here we compare messenger RNA profiles of 1,454 metabolic enzymes across 1,981 tumours spanning 19 cancer types to identify enzymes that are consistently differentially expressed....
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Full title
Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer
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TN_cdi_swepub_primary_oai_swepub_ki_se_524173
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_524173
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ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms4128
