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Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased I...

Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased I...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_524591

Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased IL-22 Production in T Cells

About this item

Full title

Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased IL-22 Production in T Cells

Publisher

United States: Elsevier Inc

Journal title

Journal of investigative dermatology, 2014-06, Vol.134 (6), p.1535-1541

Language

English

Formats

Publication information

Publisher

United States: Elsevier Inc

More information

Scope and Contents

Contents

Most psoriasis susceptibility genes were identified in cohorts of mixed clinical phenotypes and the exploration of genes in clinical subtypes is scarce. IL-22 has an established role in host defense and in psoriasis skin pathology, reflecting the delicate balance between control of infection and immunopathology. In a case–control study, we compared...

Alternative Titles

Full title

Genetic Variants of the IL22 Promoter Associate to Onset of Psoriasis before Puberty and Increased IL-22 Production in T Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_524591

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_524591

Other Identifiers

ISSN

0022-202X,1523-1747

E-ISSN

1523-1747

DOI

10.1038/jid.2014.5