VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen for...
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation
About this item
Full title
Author / Creator
Hayashi, Makoto , Majumdar, Arindam , Li, Xiujuan , Adler, Jeremy , Sun, Zuyue , Vertuani, Simona , Hellberg, Carina , Mellberg, Sofie , Koch, Sina , Dimberg, Anna , Young Koh, Gou , Dejana, Elisabetta , Belting, Heinz-Georg , Affolter, Markus , Thurston, Gavin , Holmgren, Lars , Vestweber, Dietmar and Claesson-Welsh, Lena
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Vascular endothelial growth factor (VEGF) guides the path of new vessel sprouts by inducing VEGF receptor-2 activity in the sprout tip. In the stalk cells of the sprout, VEGF receptor-2 activity is downregulated. Here, we show that VEGF receptor-2 in stalk cells is dephosphorylated by the endothelium-specific vascular endothelial-phosphotyrosine ph...
Alternative Titles
Full title
VE-PTP regulates VEGFR2 activity in stalk cells to establish endothelial cell polarity and lumen formation
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_530182
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_530182
Other Identifiers
ISSN
2041-1723
E-ISSN
2041-1723
DOI
10.1038/ncomms2683
