CD4⁺ cell-dependent granuloma formation in humanized mice infected with mycobacteria
CD4⁺ cell-dependent granuloma formation in humanized mice infected with mycobacteria
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Publisher
United States: National Academy of Sciences
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Language
English
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Publisher
United States: National Academy of Sciences
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We have used humanized mice, in which human immune cells differentiate de novo from transplanted cord blood progenitor cells, to study the human immune responses to infection with Mycobacterium bovis bacillus Calmette–Guérin and Mycobacterium tuberculosis . Granulomas with a core containing giant cells, human CD68 ⁺ macrophages, and high bacilli nu...
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Full title
CD4⁺ cell-dependent granuloma formation in humanized mice infected with mycobacteria
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_530290
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_530290
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1219985110
