Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities
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Publisher
Cambridge, UK: Cambridge University Press
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Language
English
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Publisher
Cambridge, UK: Cambridge University Press
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Contents
Monoamine oxidase A (MAOA) harbours a polymorphic upstream variable-number tandem repeat (u-VNTR). The MAOA-L allele of the u-VNTR leads to decreased gene expression levels in vitro and has been found to increase the risk of conduct disorder in males with childhood adversities. Early-life adversities have been associated with hypermethylation of th...
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Full title
Genetic and epigenetic associations of MAOA and NR3C1 with depression and childhood adversities
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TN_cdi_swepub_primary_oai_swepub_ki_se_531091
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_531091
Other Identifiers
ISSN
1461-1457
E-ISSN
1469-5111
DOI
10.1017/S1461145713000102
