The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration w...
The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Springer-Verlag
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Contents
YF476 differs from the proton pump inhibitor (PPI) esomeprazole in mode of action by antagonizing the type 2 receptor of cholecystokinin/gastrin (CCK-2R). YF476 protection against diclofenac-induced gastric ulcers was compared to esomeprazole and correlated with plasma levels of hormones related to gastric pH (gastrin, ghrelin, and somatostatin), g...
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Full title
The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_533172
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_533172
Other Identifiers
ISSN
0028-1298,1432-1912
E-ISSN
1432-1912
DOI
10.1007/s00210-012-0812-5