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Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_536899

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

About this item

Full title

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Publisher

Washington, DC: American Association for the Advancement of Science

Journal title

Science (American Association for the Advancement of Science), 2012-05, Vol.336 (6084), p.1040-1044

Language

English

Formats

Publication information

Publisher

Washington, DC: American Association for the Advancement of Science

More information

Scope and Contents

Contents

Metabolic reprogramming has been proposed to be a hallmark of cancer, yet a systematic characterization of the metabolic pathways active in transformed cells is currently lacking. Using mass spectrometry, we measured the consumption and release (CORE) profiles of 219 metabolites from media across the NCI-60 cancer cell lines, and integrated these d...

Alternative Titles

Full title

Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_536899

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_536899

Other Identifiers

ISSN

0036-8075

E-ISSN

1095-9203

DOI

10.1126/science.1218595