Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
About this item
Full title
Author / Creator
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The APOE4-mediated proinflammatory pathway is shown to initiate blood–brain barrier breakdown and resulting neurodegeneration in transgenic mice.
Restoring the blood–brain barrier
There are known connections between the Alzheimer's-disease-linked
APOE4
gene and cerebrovascular integrity. However, the mechanisms that drive known blood–br...
Alternative Titles
Full title
Apolipoprotein E controls cerebrovascular integrity via cyclophilin A
Authors, Artists and Contributors
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_536934
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_536934
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature11087
