Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
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Publisher
Washington, DC: American Association for the Advancement of Science
Journal title
Language
English
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Publisher
Washington, DC: American Association for the Advancement of Science
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Scope and Contents
Contents
Eukaryotic cells require iron for survival and have developed regulatory mechanisms for maintaining appropriate intracellular iron concentrations. The degradation of iron regulatory protein 2 (IRP2) in iron-replete cells is a key event in this pathway, but the E3 ubiquitin ligase responsible for its proteolysis has remained elusive. We found that a...
Alternative Titles
Full title
Control of Iron Homeostasis by an Iron-Regulated Ubiquitin Ligase
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_555841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_555841
Other Identifiers
ISSN
0036-8075,1095-9203
E-ISSN
1095-9203
DOI
10.1126/science.1176333
