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Loss of the Ca 2+ /calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances b...

Loss of the Ca 2+ /calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances b...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_561352

Loss of the Ca 2+ /calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine

About this item

Full title

Loss of the Ca 2+ /calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine

Journal title

Proceedings of the National Academy of Sciences - PNAS, 2008-11, Vol.105 (45), p.17549-17554

Language

English

Formats

More information

Scope and Contents

Contents

The persistent nature of addiction has been associated with activity-induced plasticity of neurons within the striatum and nucleus accumbens (NAc). To identify the molecular processes leading to these adaptations, we performed Cre/loxP-mediated genetic ablations of two key regulators of gene expression in response to activity, the Ca
2+
/calm...

Alternative Titles

Full title

Loss of the Ca 2+ /calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_561352

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_561352

Other Identifiers

ISSN

0027-8424

E-ISSN

1091-6490

DOI

10.1073/pnas.0803959105

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