A new class of nitric oxide‐releasing derivatives of cetirizine; pharmacological profile in vascular...
A new class of nitric oxide‐releasing derivatives of cetirizine; pharmacological profile in vascular and airway smooth muscle preparations
About this item
Full title
Author / Creator
Larsson, A‐K , Fumagalli, F , DiGennaro, A , Andersson, M , Lundberg, J , Edenius, C , Govoni, M , Monopoli, A , Sala, A , Dahlén, S‐E and Folco, G C
Publisher
Oxford, UK: Blackwell Publishing Ltd
Journal title
Language
English
Formats
Publication information
Publisher
Oxford, UK: Blackwell Publishing Ltd
Subjects
More information
Scope and Contents
Contents
Background and purpose:
The pharmacological properties of compounds NCX 1512 and NCX 1514, synthesized by linking the histamine H1‐receptor antagonist cetirizine to NO‐releasing spacer groups, are reported. The aim was to establish if the compounds retained the antihistamine action of the parent compound, to assess their efficacy as NO donors an...
Alternative Titles
Full title
A new class of nitric oxide‐releasing derivatives of cetirizine; pharmacological profile in vascular and airway smooth muscle preparations
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_571218
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_571218
Other Identifiers
ISSN
0007-1188
E-ISSN
1476-5381
DOI
10.1038/sj.bjp.0707214
