Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Linking p53 and ageing
A paper published in
Nature
in January 2002 caught the attention of those working on both ageing and cancer researcher: mice with a hyperactive p53 tumour suppressor gene were resistant to cancer but, here was the surprise, also showed signs of premature ageing. The link between p53 signalling and ageing is further e...
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Full title
Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation
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TN_cdi_swepub_primary_oai_swepub_ki_se_579630
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_579630
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/nature04019
