Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhi...
Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion
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Publisher
United States: Springer Nature B.V
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English
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Publisher
United States: Springer Nature B.V
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Abnormally hyperphosphorylated tau which is the major protein subunit of paired helical filaments (PHF)/neurofibrillary tangles is the pivotal lesion in Alzheimer disease (AD) and related tauopathies. The cosegregation of tau mutations with disease in inherited cases of frontotemporal dementia has confirmed that abnormalities in this protein can be...
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Significance and mechanism of Alzheimer neurofibrillary degeneration and therapeutic targets to inhibit this lesion
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TN_cdi_swepub_primary_oai_swepub_ki_se_592710
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_592710
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ISSN
0895-8696
E-ISSN
1559-1166
DOI
10.1007/s12031-002-0017-3
