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Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_593893

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

About this item

Full title

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

Publisher

England: Nature Publishing Group

Journal title

Oncogene, 2002-06, Vol.21 (26), p.4181-4190

Language

English

Formats

Publication information

Publisher

England: Nature Publishing Group

More information

Scope and Contents

Contents

The chromosomal translocation t(X;18)(p11.2;q11.2) is tightly linked to the tumorigenesis of synovial sarcoma. Through this translation the SYT gene on chromosome 18 is fused with a testis/cancer antigen gene on the X chromosome, generating either a SYT-SSX1, SYT-SSX2, or less often a SYT-SSX4 fusion gene. It has been anticipated that the individua...

Alternative Titles

Full title

Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_593893

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_593893

Other Identifiers

ISSN

0950-9232,1476-5594

E-ISSN

1476-5594

DOI

10.1038/sj.onc.1205569

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