Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
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Author / Creator
Yang, Ke , Lui, Weng-Onn , Xie, Yuntao , Zhang, Anju , Skytting, Björn , Mandahl, Nils , Larsson, Catharina , Larsson, Olle , Faculty of Medicine , Medicinska fakulteten , Lund University , Division of Clinical Genetics , Institutionen för laboratoriemedicin , Department of Laboratory Medicine , Avdelningen för klinisk genetik and Lunds universitet
Publisher
England: Nature Publishing Group
Journal title
Language
English
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Publisher
England: Nature Publishing Group
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Scope and Contents
Contents
The chromosomal translocation t(X;18)(p11.2;q11.2) is tightly linked to the tumorigenesis of synovial sarcoma. Through this translation the SYT gene on chromosome 18 is fused with a testis/cancer antigen gene on the X chromosome, generating either a SYT-SSX1, SYT-SSX2, or less often a SYT-SSX4 fusion gene. It has been anticipated that the individua...
Alternative Titles
Full title
Co-existence of SYT-SSX1 and SYT-SSX2 fusions in synovial sarcomas
Authors, Artists and Contributors
Author / Creator
Lui, Weng-Onn
Xie, Yuntao
Zhang, Anju
Skytting, Björn
Mandahl, Nils
Larsson, Catharina
Larsson, Olle
Faculty of Medicine
Medicinska fakulteten
Lund University
Division of Clinical Genetics
Institutionen för laboratoriemedicin
Department of Laboratory Medicine
Avdelningen för klinisk genetik
Lunds universitet
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_593893
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_593893
Other Identifiers
ISSN
0950-9232,1476-5594
E-ISSN
1476-5594
DOI
10.1038/sj.onc.1205569
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