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Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_597324

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

About this item

Full title

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

Publisher

Austria: Springer Nature B.V

Journal title

Amino acids, 2001-01, Vol.20 (4), p.353-362

Language

English

Formats

Publication information

Publisher

Austria: Springer Nature B.V

More information

Scope and Contents

Contents

Inhibitors of kynurenine 3-hydroxylase have previously been used to increase endogenous levels of kynurenic acid, an excitatory amino acid receptor antagonist. In the present electrophysiological study PNU 156561A was utilized to elevate endogenous concentrations of kynurenic acid and subsequent effects on the firing pattern of dopamine (DA) neuron...

Alternative Titles

Full title

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_597324

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_597324

Other Identifiers

ISSN

0939-4451

E-ISSN

1438-2199

DOI

10.1007/s007260170032

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