Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons
Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons
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Author / Creator
Erhardt, S. , Öberg, H. , Mathé, J. M. and Engberg, G.
Publisher
Austria: Springer Nature B.V
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Language
English
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Publisher
Austria: Springer Nature B.V
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Contents
Inhibitors of kynurenine 3-hydroxylase have previously been used to increase endogenous levels of kynurenic acid, an excitatory amino acid receptor antagonist. In the present electrophysiological study PNU 156561A was utilized to elevate endogenous concentrations of kynurenic acid and subsequent effects on the firing pattern of dopamine (DA) neuron...
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Full title
Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons
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TN_cdi_swepub_primary_oai_swepub_ki_se_597324
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_597324
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ISSN
0939-4451
E-ISSN
1438-2199
DOI
10.1007/s007260170032