Bactericidal antisense effects of peptide–PNA conjugates
Bactericidal antisense effects of peptide–PNA conjugates
About this item
Full title
Author / Creator
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Antisense peptide nucleic acids (PNAs) can specifically inhibit
Escherichia coli
gene expression and growth and hold promise as anti-infective agents and as tools for microbial functional genomics. Here we demonstrate that chemical modification improves the potency of standard PNAs. We show that 9- to 12-mer PNAs, especially when attached to...
Alternative Titles
Full title
Bactericidal antisense effects of peptide–PNA conjugates
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_598494
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_598494
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/86753
