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Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_630014

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals

About this item

Full title

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals

Publisher

US: Oxford University Press

Journal title

Molecular biology and evolution, 2023-06, Vol.40 (6)

Language

English

Formats

Publication information

Publisher

US: Oxford University Press

More information

Scope and Contents

Contents

Abstract
Dupuytren's disease is characterized by fingers becoming permanently bent in a flexed position. Whereas people of African ancestry are rarely afflicted by Dupuytren's disease, up to ∼30% of men over 60 years suffer from this condition in northern Europe. Here, we meta-analyze 3 biobanks comprising 7,871 cases and 645,880 controls and fi...

Alternative Titles

Full title

Major Genetic Risk Factors for Dupuytren's Disease Are Inherited From Neandertals

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_630014

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_630014

Other Identifiers

ISSN

0737-4038,1537-1719

E-ISSN

1537-1719

DOI

10.1093/molbev/msad130