Landscape of BCL2 Resistance Mutations in a Real-World Cohort of Patients with Relapsed/Refractory C...
Landscape of BCL2 Resistance Mutations in a Real-World Cohort of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Treated with Venetoclax
About this item
Full title
Author / Creator
Kotmayer, Lili , László, Tamás , Mikala, Gábor , Kiss, Richárd , Lévay, Luca , Hegyi, Lajos László , Gróf, Stefánia , Nagy, Tibor , Barna, Gábor , Farkas, Péter , Weisinger, Júlia , Nagy, Zsolt , Balogh, Alexandra , Masszi, Tamás , Demeter, Judit , Sulák, Adrienn , Kohl, Zoltán , Alizadeh, Hussain , Egyed, Miklós , Pettendi, Piroska , Gergely, Lajos , Plander, Márk , Pauker, Zsolt , Masszi, András , Matolcsy, András , Szász, Róbert , Bödör, Csaba and Alpár, Donát
Publisher
Switzerland: MDPI AG
Journal title
Language
English
Formats
Publication information
Publisher
Switzerland: MDPI AG
Subjects
More information
Scope and Contents
Contents
The oral, highly selective Bcl2 inhibitor venetoclax has substantially improved the therapeutic landscape of chronic lymphocytic leukemia (CLL). Despite the remarkable response rates in patients with relapsed/refractory (R/R) disease, acquired resistance is the leading cause of treatment failure, with somatic
mutations being the predominant gene...
Alternative Titles
Full title
Landscape of BCL2 Resistance Mutations in a Real-World Cohort of Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia Treated with Venetoclax
Authors, Artists and Contributors
Author / Creator
László, Tamás
Mikala, Gábor
Kiss, Richárd
Lévay, Luca
Hegyi, Lajos László
Gróf, Stefánia
Nagy, Tibor
Barna, Gábor
Farkas, Péter
Weisinger, Júlia
Nagy, Zsolt
Balogh, Alexandra
Masszi, Tamás
Demeter, Judit
Sulák, Adrienn
Kohl, Zoltán
Alizadeh, Hussain
Egyed, Miklós
Pettendi, Piroska
Gergely, Lajos
Plander, Márk
Pauker, Zsolt
Masszi, András
Matolcsy, András
Szász, Róbert
Bödör, Csaba
Alpár, Donát
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_668632
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_668632
Other Identifiers
ISSN
1422-0067,1661-6596
E-ISSN
1422-0067
DOI
10.3390/ijms24065802
