Klotho controls the brain–immune system interface in the choroid plexus
Klotho controls the brain–immune system interface in the choroid plexus
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Publisher
United States: National Academy of Sciences
Journal title
Language
English
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Publisher
United States: National Academy of Sciences
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Scope and Contents
Contents
Located within the brain’s ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood. For unknown reasons, the choroid plexus produces high levels of the protein klotho. Here, we show that these levels naturally decline with aging. Depleting klotho selectively from th...
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Full title
Klotho controls the brain–immune system interface in the choroid plexus
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Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_699367
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_699367
Other Identifiers
ISSN
0027-8424,1091-6490
E-ISSN
1091-6490
DOI
10.1073/pnas.1808609115
