Multivalent insulin receptor activation using insulin–DNA origami nanostructures
Multivalent insulin receptor activation using insulin–DNA origami nanostructures
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Insulin binds the insulin receptor (IR) and regulates anabolic processes in target tissues. Impaired IR signalling is associated with multiple diseases, including diabetes, cancer and neurodegenerative disorders. IRs have been reported to form nanoclusters at the cell membrane in several cell types, even in the absence of insulin binding. Here we e...
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Full title
Multivalent insulin receptor activation using insulin–DNA origami nanostructures
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TN_cdi_swepub_primary_oai_swepub_ki_se_824162
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_824162
Other Identifiers
ISSN
1748-3387
E-ISSN
1748-3395
DOI
10.1038/s41565-023-01507-y
