Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lympho...
Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia
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Author / Creator
Dam, Merete , Centanni, Maddalena , Friberg, Lena E. , Centanni, Daniel , Karlsson, Mats O. , Stensig Lynggaard, Line , Johannsdottir, Inga Maria , Wik, Hilde Skuterud , Malmros, Johan , Vaitkeviciene, Goda Elizabeta , Griskevicius, Laimonas , Hallböök, Helene , Jónsson, Ólafur Gísli , Overgaard, Ulrik , Schmiegelow, Kjeld , Hansen, Stefan Nygaard , Heyman, Mats and Albertsen, Birgitte Klug
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Asparaginase is an essential component of acute lymphoblastic leukemia (ALL) therapy, yet its associated toxicities often lead to treatment discontinuation, increasing the risk of relapse. Hypersensitivity reactions include clinical allergies, silent inactivation, or allergy-like responses. We hypothesized that even moderate increases in asparagina...
Alternative Titles
Full title
Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia
Authors, Artists and Contributors
Author / Creator
Centanni, Maddalena
Friberg, Lena E.
Centanni, Daniel
Karlsson, Mats O.
Stensig Lynggaard, Line
Johannsdottir, Inga Maria
Wik, Hilde Skuterud
Malmros, Johan
Vaitkeviciene, Goda Elizabeta
Griskevicius, Laimonas
Hallböök, Helene
Jónsson, Ólafur Gísli
Overgaard, Ulrik
Schmiegelow, Kjeld
Hansen, Stefan Nygaard
Heyman, Mats
Albertsen, Birgitte Klug
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_843910
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_843910
Other Identifiers
ISSN
0887-6924,1476-5551
E-ISSN
1476-5551
DOI
10.1038/s41375-024-02153-6