Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab)...
Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies
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Author / Creator
Kretzschmar, Genia , Páez, Laura Piñero , Tan, Ziyang , Wang, Jun , Gonzalez, Laura , Mugabo, Constantin Habimana , Johnsson, Anette , Chen, Yang , Mikeš, Jaromír , Lakshmikanth, Tadepally , James, Anna , Goldbach-Mansky, Raphaela , Fischer, Marie , Palmblad, Karin , Alehashemi, Sara , Horne, AnnaCarin and Brodin, Petter
Publisher
New York: Springer US
Journal title
Language
English
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Publication information
Publisher
New York: Springer US
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Scope and Contents
Contents
Purpose
A causal role of type-I interferons (IFN-I) in autoinflammatory type-I interferonopathies such as SAVI (STING–associated vasculopathy with onset in infancy) and CANDLE (chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperatures) is suggested by elevated expression of IFN-I stimulated genes (ISGs). Hitherto, the...
Alternative Titles
Full title
Normalized Interferon Signatures and Clinical Improvements by IFNAR1 Blocking Antibody (Anifrolumab) in Patients with Type I Interferonopathies
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_887249
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_887249
Other Identifiers
ISSN
0271-9142,1573-2592
E-ISSN
1573-2592
DOI
10.1007/s10875-024-01826-2
