Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis
Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis
About this item
Full title
Author / Creator
Publisher
London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title
Language
English
Formats
Publication information
Publisher
London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Subjects
More information
Scope and Contents
Contents
BackgroundHepatocyte-specific NEMO/NF-κB deleted mice (NEMOΔhepa) develop spontaneous non-alcoholic steatohepatitis (NASH). Free fatty acids and bile acids promote DR5 expression. TRAIL/NK cell-mediated activation of TRAIL-R2/DR5 plays an important role during acute injury in NEMOΔhepa mice.AimTo inhibit the progression of NASH in the absence of he...
Alternative Titles
Full title
Nor-ursodeoxycholic acid reverses hepatocyte-specific nemo-dependent steatohepatitis
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_398772
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wageningen_narcis_oai_library_wur_nl_wurpubs_398772
Other Identifiers
ISSN
0017-5749
E-ISSN
1468-3288
DOI
10.1136/gut.2010.223834
