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白藜芦醇对颈总动脉球囊损伤术后大鼠血管的修复作用

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白藜芦醇对颈总动脉球囊损伤术后大鼠血管的修复作用

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wanfang_journals_jfjyxzz202106002

白藜芦醇对颈总动脉球囊损伤术后大鼠血管的修复作用

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Full title

白藜芦醇对颈总动脉球囊损伤术后大鼠血管的修复作用

Author / Creator

罗兰 , 熊颖 , 国奥 , 陈春意 , 夏韵 , 李靖凡 , 卢清 and 柯剑娟

Publisher

武汉大学中南医院麻醉科,武汉 430071

Journal title

解放军医学杂志, 2021, Vol.46 (6), p.538-544

Language

Chinese

Formats

Articles

Publication information

Publisher

武汉大学中南医院麻醉科,武汉 430071

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Scope and Contents

Contents

R654.3; 目的 探讨白藜芦醇(RSV)对颈总动脉球囊损伤术后大鼠血管的修复作用.方法 将40只SD大鼠随机分为假手术组、模型组、溶剂对照组(DSMO组)与RSV组,每组10只.制备左颈总动脉球囊损伤模型后,模型组不给药,DMSO组和RSV组在颈总动脉球囊损伤段外周分别给予相同剂量的溶剂DMSO和RSV.假手术组仅结扎颈外动脉.14 d后过量麻醉处死大鼠,取颈总动脉损伤段组织,HE染色观察血管内膜增生程度和管腔狭窄程度,CD31免疫组织化学染色评估血管再内皮化程度,Western blotting检测动脉组织中血管内皮生长因子(VEGF)的表达水平.结果 HE染色结果显示,各组外膜以内区(EEL)周长、EEL面积以及内膜及内区(IEL)面积差异无统计学意义(P>0.05);与假手术组和D...

Alternative Titles

Full title

白藜芦醇对颈总动脉球囊损伤术后大鼠血管的修复作用

Authors, Artists and Contributors

Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_wanfang_journals_jfjyxzz202106002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wanfang_journals_jfjyxzz202106002

Other Identifiers

ISSN

0577-7402

DOI

10.11855/j.issn.0577-7402.2021.06.02

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