多发性硬化人类白细胞抗原易感基因研究进展
多发性硬化人类白细胞抗原易感基因研究进展
Publication information
Publisher
中山大学附属第三医院神经病学科多发性硬化临床研究中心,广州,510630
Subjects
More information
Scope and Contents
Contents
多发性硬化为一种免疫相关性中枢神经系统脱髓鞘疾病,临床表现呈异质性,好发于青壮年女性,病残率高,给患者家庭及社会造成沉重负担.遗传因素和环境因素共同参与其发病机制,而HLA基因复合体为重要的遗传学决定因素,占易感风险的60%,对其研究是目前多发性硬化遗传学研究的热点和难点.
Alternative Titles
Full title
多发性硬化人类白细胞抗原易感基因研究进展
Authors, Artists and Contributors
Author / Creator
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_wanfang_journals_xdsjjbzz201202006
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wanfang_journals_xdsjjbzz201202006
Other Identifiers
ISSN
1672-6731
DOI
10.3969/j.issn.1672-6731.2012.02.006
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