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电针对神经病理性疼痛大鼠及其脊髓EAAs含量的影响

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电针对神经病理性疼痛大鼠及其脊髓EAAs含量的影响

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wanfang_journals_zjtnyx_e201102002

电针对神经病理性疼痛大鼠及其脊髓EAAs含量的影响

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Full title

电针对神经病理性疼痛大鼠及其脊髓EAAs含量的影响

Author / Creator

李翠贤 , 闫丽萍 , 易建良 , 马骋 and 王臻

Publisher

Key Laboratory of Acupuncture of Jiangsu, Nangjing University of Traditional Chinese Medicine, Nanjing 210029, P. R. China

Journal title

针灸推拿医学(英文版), 2011, Vol.9 (2), p.73-78

Language

Chinese

Formats

Articles

Publication information

Publisher

Key Laboratory of Acupuncture of Jiangsu, Nangjing University of Traditional Chinese Medicine, Nanjing 210029, P. R. China

More information

Scope and Contents

Contents

R2-03; 目的:观察电针对神经病理性疼痛大鼠痛阈及脊髓兴奋性氨基酸含量的影响,探讨电针治疗神经病理性疼痛的机制.方法:SD大鼠随机分为对照组、假模型组和造模组,采用大鼠坐骨神经分支选择性损伤(Spared Nerve Injury, SNI) 模型,造模组SNI 术后选取造模成功的大鼠再随机分为模型组、电针组、假电针组.分别于SNI术前、术后第7 天及第9 天、第6 次治疗后测定大鼠的机械痛阈和热痛阈.造模后第l0 天开始电针环跳穴与委中穴,观察其对大鼠机械痛阈和热痛阈的影响,并通过脊髓微透析技术,应用柱前衍生法+HPLC荧光检测法检测大鼠脊髓兴奋性氨基酸的含量.结果:SNI 手术可以显著降低大鼠机械痛阈,模型组大鼠脊髓微透析液中谷氨酸(Glutamate, Glu )和天门冬氨酸(As...

Alternative Titles

Full title

电针对神经病理性疼痛大鼠及其脊髓EAAs含量的影响

Authors, Artists and Contributors

Author / Creator

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Primary Identifiers

Record Identifier

TN_cdi_wanfang_journals_zjtnyx_e201102002

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_wanfang_journals_zjtnyx_e201102002

Other Identifiers

ISSN

1672-3597

DOI

10.1007/s11726-011-0475-7

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