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107 results for Diphenylamine+-+pharmacology

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Select record 21
ArticlesPeer ReviewedFull Text
c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression
Author / Creator:Sim, Wen Jing ; Iyengar, Prasanna Vasudevan ; Lama, Dilraj ; Lui, Sarah Kit Leng ; Ng, Hsien Chun ; Haviv-Shapira, Lior ; Domany, Eytan ; Kappei, Dennis ; Tan, Tuan Zea ; Saei, Azad ; Jaynes, Patrick William ; Verma, Chandra Shekhar ; Kumar, Alan Prem ; Rouanne, Mathieu ; Ha, Hong Koo ; Radulescu, Camelia ; ten Dijke, Peter ; Eichhorn, Pieter Johan Adam ; Thiery, Jean Paul
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4349-19, Article 4349
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Generation of human antral and fundic gastric organoids from pluripotent stem cells
Author / Creator:Broda, Taylor R. ; McCracken, Kyle W. ; Wells, James M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2019-01, Vol.14 (1), p.28-50
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Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer
Author / Creator:Pek, M ; Yatim, S M J M ; Chen, Y ; Li, J ; Gong, M ; Jiang, X ; Zhang, F ; Zheng, J ; Wu, X ; Yu, Q
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2017-08, Vol.36 (35), p.4975-4986
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Synthesis and In Vitro Evaluation as Potential Anticancer and Antioxidant Agents of Diphenylamine-Pyrrolidin-2-one-Hydrazone Derivatives
Author / Creator:Zubrickė, Irma ; Jonuškienė, Ilona ; Kantminienė, Kristina ; Tumosienė, Ingrida ; Petrikaitė, Vilma
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-12, Vol.24 (23), p.16804
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Quantitative Live Imaging Reveals Phase Dependency of PDAC Patient‐Derived Organoids on ERK and AMPK Activity
Author / Creator:Tsukamoto, Shoko ; Huaze, Ye ; Weisheng, Zhang ; Machinaga, Akihito ; Kakiuchi, Nobuyuki ; Ogawa, Seishi ; Seno, Hiroshi ; Higashiyama, Shigeki ; Matsuda, Michiyuki ; Hiratsuka, Toru
Publisher:England: John Wiley & Sons, Inc
Journal title:Cancer science, 2025-03, Vol.116 (3), p.724-735
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Vitamin C and MEK Inhibitor PD0325901 Synergistically Promote Oligodendrocytes Generation by Promoting DNA Demethylation
Author / Creator:Ren, Xinyue ; Yang, Ying ; Wang, Min ; Yuan, Qianting ; Suo, Na ; Xie, Xin
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-12, Vol.29 (24), p.5939
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In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents
Author / Creator:Shah, Aviral ; Desai, Kathan ; Bhanusali, Ajaykumar ; Agrawal, Shikha ; Patel, Khushbu ; Naik, Nilesh ; Thakar, Anuj ; Naik, Hem ; Kanjariya, Dilip ; Malek, Naved ; Jauhari, Smita ; Kadam, Yogesh ; Patel, Bhavesh ; Shah, Ankit B.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-05, Vol.15 (1), p.18928-19
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Dissection of two routes to naïve pluripotency using different kinase inhibitors
Author / Creator:Martinez-Val, Ana ; Lynch, Cian J. ; Calvo, Isabel ; Ximénez-Embún, Pilar ; Garcia, Fernando ; Zarzuela, Eduardo ; Serrano, Manuel ; Munoz, Javier
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1863-16, Article 1863
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Ethylene –dependent and –independent superficial scald resistance mechanisms in ‘Granny Smith’ apple fruit
Author / Creator:Karagiannis, Evangelos ; Michailidis, Michail ; Tanou, Georgia ; Samiotaki, Martina ; Karamanoli, Katerina ; Avramidou, Evangelia ; Ganopoulos, Ioannis ; Madesis, Panagiotis ; Molassiotis, Athanassios
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-07, Vol.8 (1), p.11436-16, Article 11436
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ArticlesPeer ReviewedFull Text
Role of yes-associated protein 1, angiomotin, and mitogen-activated kinase kinase 1/2 in development of the bovine blastocyst
Author / Creator:Negrón-Pérez, Verónica M ; Hansen, Peter J
Publisher:United States: Society for the Study of Reproduction
Journal title:Biology of reproduction, 2018-02, Vol.98 (2), p.170-183
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ArticlesPeer ReviewedFull Text
N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties
Author / Creator:Qian, X ; Anzovino, A ; Kim, S ; Suyama, K ; Yao, J ; Hulit, J ; Agiostratidou, G ; Chandiramani, N ; McDaid, H M ; Nagi, C ; Cohen, H W ; Phillips, G R ; Norton, L ; Hazan, R B
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2014-06, Vol.33 (26), p.3411-3421
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Select record 32
ArticlesPeer ReviewedFull Text
Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice
Author / Creator:Chang, Tiffany ; Krisman, Kimberly ; Theobald, Emily Harding ; Xu, Jin ; Akutagawa, Jon ; Lauchle, Jennifer O. ; Kogan, Scott ; Braun, Benjamin S. ; Shannon, Kevin
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-01, Vol.123 (1), p.335-339
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Select record 33
ArticlesPeer ReviewedFull Text
A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer
Author / Creator:Wainberg, Zev A. ; Alsina, Maria ; Soares, Heloisa P. ; Braña, Irene ; Britten, Carolyn D. ; Del Conte, Gianluca ; Ezeh, Patrick ; Houk, Brett ; Kern, Kenneth A. ; Leong, Stephen ; Pathan, Nuzhat ; Pierce, Kristen J. ; Siu, Lillian L. ; Vermette, Jennifer ; Tabernero, Josep
Publisher:Cham: Springer International Publishing
Journal title:Targeted oncology, 2017-12, Vol.12 (6), p.775-785
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Select record 34
ArticlesPeer ReviewedFull Text
Hypoxia-inducible factor-2 alpha promotes the proliferation of human placenta-derived mesenchymal stem cells through the MAPK/ERK signaling pathway
Author / Creator:Zhu, Chengxing ; Yu, Jiong ; Pan, Qiaoling ; Yang, Jinfeng ; Hao, Guangshu ; Wang, Yingjie ; Li, Lanjuan ; Cao, Hongcui
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-10, Vol.6 (1), p.35489, Article 35489
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Select record 35
ArticlesPeer ReviewedFull Text
Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model
Author / Creator:Xia, Yifeng ; Yeddula, Narayana ; Leblanc, Mathias ; Ke, Eugene ; Zhang, Yonghui ; Oldfield, Eric ; Shaw, Reuben J. ; Verma, Inder M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2012-03, Vol.14 (3), p.257-265
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Select record 36
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MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex
Author / Creator:KONOPLEVA, M ; MILELLA, M ; MAK, D. H ; CHEN, W ; MCCUBREY, J ; TAFURI, A ; ANDREEFF, M ; RUVOLO, P ; WATTS, J. C ; RICCIARDI, M. R ; KORCHIN, B ; MCQUEEN, T ; BORNMANN, W ; TSAO, T ; BERGAMO, P
Publisher:Avenel, NJ: Nature Publishing Group
Journal title:Leukemia, 2012-04, Vol.26 (4), p.778-787
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Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo
Author / Creator:Houweling, M. ; Abdul, U. K. ; Brahm, C. ; Lagerweij, T. ; Heukelom, S. ; Koken, P. W. ; Honeywell, R. ; Wedekind, L. E. ; Peters, G. J. ; Verheul, H. ; Sminia, P. ; Noske, D. ; Wurdinger, T. ; Westerman, B. A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2023-01, Vol.149 (1), p.297-305
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Select record 38
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Co-targeting PI3K/Akt and MAPK/ERK pathways leads to an enhanced antitumor effect on human hypopharyngeal squamous cell carcinoma
Author / Creator:Peng, Xiaolin ; Liu, Yao ; Zhu, Shan ; Peng, Xin ; Li, Hui ; Jiao, Wenhui ; Lin, Peng ; Zhang, Zhe ; Qiu, Yuling ; Jin, Meihua ; Wang, Ran ; Kong, Dexin
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2019-12, Vol.145 (12), p.2921-2936
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Select record 39
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An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery
Author / Creator:Willoughby, Lee F. ; Schlosser, Tanja ; Manning, Samuel A. ; Parisot, John P. ; Street, Ian P. ; Richardson, Helena E. ; Humbert, Patrick O. ; Brumby, Anthony M.
Publisher:England: The Company of Biologists Ltd
Journal title:Disease models & mechanisms, 2013-03, Vol.6 (2), p.521-529
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Select record 40
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Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway
Author / Creator:Yang, Zejia ; Liao, Jipei ; Carter-Cooper, Brandon A. ; Lapidus, Rena G. ; Cullen, Kevin J. ; Dan, Hancai
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2019-05, Vol.19 (1), p.485-12, Article 485
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c-Met activation leads to the establishment of a TGFβ-receptor regulatory network in bladder cancer progression

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Generation of human antral and fundic gastric organoids from pluripotent stem cells

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Oncogenic KRAS-associated gene signature defines co-targeting of CDK4/6 and MEK as a viable therapeutic strategy in colorectal cancer

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Synthesis and In Vitro Evaluation as Potential Anticancer and Antioxidant Agents of Diphenylamine-Pyrrolidin-2-one-Hydrazone Derivatives

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Quantitative Live Imaging Reveals Phase Dependency of PDAC Patient‐Derived Organoids on ERK and AMPK Activity

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Vitamin C and MEK Inhibitor PD0325901 Synergistically Promote Oligodendrocytes Generation by Promoting DNA Demethylation

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In vitro and in silico evaluation of fluorinated diphenylamine chalcone derivatives as potential antimalarial and anticancer agents

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Dissection of two routes to naïve pluripotency using different kinase inhibitors

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Ethylene –dependent and –independent superficial scald resistance mechanisms in ‘Granny Smith’ apple fruit

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Role of yes-associated protein 1, angiomotin, and mitogen-activated kinase kinase 1/2 in development of the bovine blastocyst

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N-cadherin/FGFR promotes metastasis through epithelial-to-mesenchymal transition and stem/progenitor cell-like properties

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Sustained MEK inhibition abrogates myeloproliferative disease in Nf1 mutant mice

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A Multi-Arm Phase I Study of the PI3K/mTOR Inhibitors PF-04691502 and Gedatolisib (PF-05212384) plus Irinotecan or the MEK Inhibitor PD-0325901 in Advanced Cancer

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Hypoxia-inducible factor-2 alpha promotes the proliferation of human placenta-derived mesenchymal stem cells through the MAPK/ERK signaling pathway

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Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model

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MEK inhibition enhances ABT-737-induced leukemia cell apoptosis via prevention of ERK-activated MCL-1 induction and modulation of MCL-1/BIM complex

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Radio-sensitizing effect of MEK inhibition in glioblastoma in vitro and in vivo

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Co-targeting PI3K/Akt and MAPK/ERK pathways leads to an enhanced antitumor effect on human hypopharyngeal squamous cell carcinoma

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An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery

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Regulation of cisplatin-resistant head and neck squamous cell carcinoma by the SRC/ETS-1 signaling pathway

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