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ArticlesPeer ReviewedFull Text
PKM2 Facilitates Classical Swine Fever Virus Replication by Enhancing NS5B Polymerase Function
Author / Creator:Song, Mengzhao ; Liu, Shanchuan ; Luo, Yan ; Ji, Tiantian ; Zhang, Yanming ; Deng, Wen
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2025-04, Vol.17 (5), p.648
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StackHCV: a web-based integrative machine-learning framework for large-scale identification of hepatitis C virus NS5B inhibitors
Author / Creator:Malik, Aijaz Ahmad ; Warot, Chotpatiwetchkul ; Phanus-umporn Chuleeporn ; Nantasenamat Chanin ; Phasit, Charoenkwan ; Watshara, Shoombuatong
Publisher:Dordrecht: Springer Nature B.V
Journal title:Journal of computer-aided molecular design, 2021-10, Vol.35 (10), p.1037-1053
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Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C
Author / Creator:Ahmed, Hala Rady ; Waly, Nancy G. F. M. ; Abd El-Baky, Rehab Mahmoud ; Yahia, Ramadan ; Hetta, Helal F. ; Elsayed, Amr M. ; Ibrahem, Reham Ali
Publisher:United States: Public Library of Science
Journal title:PloS one, 2021-04, Vol.16 (4), p.e0249770
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microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3′ untranslated region: function in replication and influence of RNA secondary structure
Author / Creator:Gerresheim, Gesche K. ; Dünnes, Nadia ; Nieder-Röhrmann, Anika ; Shalamova, Lyudmila A. ; Fricke, Markus ; Hofacker, Ivo ; Höner zu Siederdissen, Christian ; Marz, Manja ; Niepmann, Michael
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2017-02, Vol.74 (4), p.747-760
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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors
Author / Creator:Boyce, Sarah E. ; Tirunagari, Neeraj ; Niedziela-Majka, Anita ; Perry, Jason ; Wong, Melanie ; Kan, Elaine ; Lagpacan, Leanna ; Barauskas, Ona ; Hung, Magdeleine ; Fenaux, Martijn ; Appleby, Todd ; Watkins, William J. ; Schmitz, Uli ; Sakowicz, Roman
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014, Vol.9 (1), p.e84808
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Diversity of the hepatitis C virus NS5B gene during HIV co-infection
Author / Creator:Ngwaga, Tshegofatso ; Kong, Ling ; Lin, Derrick ; Schoborg, Cassandra ; Taylor, Lynn E. ; Mayer, Kenneth H. ; Klein, Robert S. ; Celentano, David D. ; Sobel, Jack D. ; Jamieson, Denise J. ; King, Caroline C. ; Tavis, John E. ; Blackard, Jason T.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0237162
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Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein
Author / Creator:Lee, Chang Ho ; Lee, Soo-Han ; Kim, Ji Hyun ; Noh, Yook-Hwan ; Noh, Gyu-Jeong ; Lee, Seong-Wook
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2015-10, Vol.4 (10), p.e254-e254, Article e254
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Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking
Author / Creator:Wei, Yu ; Li, Jinlong ; Qing, Jie ; Huang, Mingjie ; Wu, Ming ; Gao, Fenghua ; Li, Dongmei ; Hong, Zhangyong ; Kong, Lingbao ; Huang, Weiqiang ; Lin, Jianping
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-02, Vol.11 (2), p.e0148181
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Using NS5B Sequencing for Hepatitis C Virus Genotyping Reveals Discordances with Commercial Platforms
Author / Creator:Chueca, Natalia ; Rivadulla, Isidro ; Lovatti, Rubén ; Reina, Gabriel ; Blanco, Ana ; Fernandez-Caballero, Jose Angel ; Cardeñoso, Laura ; Rodriguez-Granjer, Javier ; Fernandez-Alonso, Miriam ; Aguilera, Antonio ; Alvarez, Marta ; Galán, Juan Carlos ; García, Federico
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-04, Vol.11 (4), p.e0153754
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Prevalence and Pattern of Resistance in NS5A/NS5B in Hepatitis C Chronic Patients Genotype 3 Examined at a Public Health Laboratory in the State of São Paulo, Brazil
Author / Creator:de Torres Santos, Ana Paula ; Martins Silva, Vanessa Cristina ; Mendes-Corrêa, Maria Cássia ; Lemos, Marcilio Figueiredo ; de Mello Malta, Fernanda ; Santana, Rúbia Anita Ferraz ; Dastoli, Gregório Tadeu Fernando ; de Castro, Vanessa Fusco Duarte ; Pinho, João Renato Rebello ; Moreira, Regina Célia
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Infection and drug resistance, 2021-01, Vol.14, p.723-730
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Difluoromethylornithine (DFMO), an Inhibitor of Polyamine Biosynthesis, and Antioxidant N-Acetylcysteine Potentiate Immune Response in Mice to the Recombinant Hepatitis C Virus NS5B Protein
Author / Creator:Lesnova, Ekaterina I. ; Masalova, Olga V. ; Permyakova, Kristina Yu ; Kozlov, Vyacheslav V. ; Nikolaeva, Tatyana N. ; Pronin, Alexander V. ; Valuev-Elliston, Vladimir T. ; Ivanov, Alexander V. ; Kushch, Alla A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-06, Vol.22 (13), p.6892
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ArticlesPeer ReviewedFull Text
Distinct Characteristic Binding Modes of Benzofuran Core Inhibitors to Diverse Genotypes of Hepatitis C Virus NS5B Polymerase: A Molecular Simulation Study
Author / Creator:Han, Di ; Zhao, Fang ; Chen, Yifan ; Xue, Yiwei ; Bao, Ke ; Chang, Yuxiao ; Lu, Jiarui ; Wang, Meiting ; Liu, Taigang ; Gao, Qinghe ; Cui, Wei ; Xu, Yongtao
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (15), p.8028
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Select record 33
ArticlesPeer ReviewedFull Text
PPP2R5D promotes hepatitis C virus infection by binding to viral NS5B and enhancing viral RNA replication
Author / Creator:Anwar, Muhammad Ikram ; Li, Ni ; Zhou, Qing ; Chen, Mingxiao ; Hu, Chengguang ; Wu, Tao ; Chen, Haihang ; Li, Yi-Ping ; Zhou, Yuanping
Publisher:London: BioMed Central Ltd
Journal title:Virology journal, 2022-07, Vol.19 (1), p.118-118, Article 118
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Screening and molecular docking of selected phytochemicals against NS5B polymerase of hepatitis c virus
Author / Creator:Mustafa, Ghulam ; Majid, Muhammad ; Ghaffar, Abdul ; Yameen, Muhammad ; Samad, Hafiz Abdul ; Mahrosh, Hafiza Salaha
Publisher:Pakistan
Journal title:Pakistan journal of pharmaceutical sciences, 2020-09, Vol.33 (5(Supplementary)), p.2317
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First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients
Author / Creator:Hasanshahi, Zahra ; Hashempour, Ava ; Ghasabi, Farzane ; Moayedi, Javad ; Musavi, Zahra ; Dehghani, Behzad ; Sharafi, Heidar ; Joulaei, Hassan
Publisher:London: BioMed Central Ltd
Journal title:BMC gastroenterology, 2021-11, Vol.21 (1), p.1-14, Article 443
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Prevalence of NS5B resistance-associated variants in treatment-naïve Asian patients with chronic hepatitis C
Author / Creator:Yang, Song ; Xing, Huichun ; Feng, Shenghu ; Ju, Wei ; Liu, Shunai ; Wang, Xiaomei ; Ou, Weini ; Cheng, Jun ; Pan, Calvin Q
Publisher:Wien: Springer Nature B.V
Journal title:Archives of virology, 2018-02, Vol.163 (2), p.467-473
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Facilitating SARS CoV-2 RNA-Dependent RNA polymerase (RdRp) drug discovery by the aid of HCV NS5B palm subdomain binders: In silico approaches and benchmarking
Author / Creator:Elghoneimy, Laila K ; Ismail, Muhammad I ; Boeckler, Frank M ; Azzazy, Hassan M.E ; Ibrahim, Tamer M
Publisher:United States: Elsevier Ltd
Journal title:Computers in biology and medicine, 2021-07, Vol.134, p.104468-104468, Article 104468
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Hepatitis C virus genotyping based on Core and NS5B regions in Cameroonian patients
Author / Creator:Tagnouokam-Ngoupo, Paul Alain ; Ngoufack, Marie Nicole ; Kenmoe, Sebastien ; Lissock, Simon Frédéric ; Amougou-Atsama, Marie ; Banai, Robert ; Ngono, Laure ; Njouom, Richard
Publisher:England: BioMed Central Ltd
Journal title:Virology journal, 2019-08, Vol.16 (1), p.101-101, Article 101
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Synthesis of baicalin carboxylate derivatives and their structure-Activity relationship analysis of their inhibitory activity on BVDV NS5B polymerase
Author / Creator:Zong, Ying ; Sun, Yu ; Che, Yi ; Wang, Hui ; Shi, Kun ; He, Zhong ; Du, Rui
Publisher:London: Wolters Kluwer India Pvt. Ltd
Journal title:Pharmacognosy Magazine, 2022-07, Vol.18 (79), p.611-620
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Cell Penetrable Humanized-VH/VHH That Inhibit RNA Dependent RNA Polymerase (NS5B) of HCV
Author / Creator:Thueng-in, Kanyarat ; Thanongsaksrikul, Jeeraphong ; Srimanote, Potjanee ; Bangphoomi, Kunan ; Poungpair, Ornnuthchar ; Maneewatch, Santi ; Choowongkomon, Kiattawee ; Chaicumpa, Wanpen
Publisher:San Francisco: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e49254
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Showing 21 to 40 of 1,353 results

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PKM2 Facilitates Classical Swine Fever Virus Replication by Enhancing NS5B Polymerase Function

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StackHCV: a web-based integrative machine-learning framework for large-scale identification of hepatitis C virus NS5B inhibitors

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Distribution of naturally -occurring NS5B resistance-associated substitutions in Egyptian patients with chronic Hepatitis C

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microRNA-122 target sites in the hepatitis C virus RNA NS5B coding region and 3′ untranslated region: function in replication and influence of RNA secondary structure

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Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors

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Diversity of the hepatitis C virus NS5B gene during HIV co-infection

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Pharmacokinetics of a Cholesterol-conjugated Aptamer Against the Hepatitis C Virus (HCV) NS5B Protein

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Discovery of Novel Hepatitis C Virus NS5B Polymerase Inhibitors by Combining Random Forest, Multiple e-Pharmacophore Modeling and Docking

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Using NS5B Sequencing for Hepatitis C Virus Genotyping Reveals Discordances with Commercial Platforms

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Prevalence and Pattern of Resistance in NS5A/NS5B in Hepatitis C Chronic Patients Genotype 3 Examined at a Public Health Laboratory in the State of São Paulo, Brazil

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Difluoromethylornithine (DFMO), an Inhibitor of Polyamine Biosynthesis, and Antioxidant N-Acetylcysteine Potentiate Immune Response in Mice to the Recombinant Hepatitis C Virus NS5B Protein

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Distinct Characteristic Binding Modes of Benzofuran Core Inhibitors to Diverse Genotypes of Hepatitis C Virus NS5B Polymerase: A Molecular Simulation Study

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PPP2R5D promotes hepatitis C virus infection by binding to viral NS5B and enhancing viral RNA replication

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Screening and molecular docking of selected phytochemicals against NS5B polymerase of hepatitis c virus

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First report on molecular docking analysis and drug resistance substitutions to approved HCV NS5A and NS5B inhibitors amongst Iranian patients

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Prevalence of NS5B resistance-associated variants in treatment-naïve Asian patients with chronic hepatitis C

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Facilitating SARS CoV-2 RNA-Dependent RNA polymerase (RdRp) drug discovery by the aid of HCV NS5B palm subdomain binders: In silico approaches and benchmarking

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Hepatitis C virus genotyping based on Core and NS5B regions in Cameroonian patients

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Synthesis of baicalin carboxylate derivatives and their structure-Activity relationship analysis of their inhibitory activity on BVDV NS5B polymerase

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Cell Penetrable Humanized-VH/VHH That Inhibit RNA Dependent RNA Polymerase (NS5B) of HCV

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