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83 results for Nedd4+Ubiquitin+Protein+Ligases+-+genetics

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ArticlesPeer ReviewedFull Text
Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy
Author / Creator:Jiang, Bin ; Bai, Fan ; Hu, Yunfu ; Ren, Yu ; Su, Yuan ; Song, Wanxuan ; Xie, Kunxin ; Wang, Dongdong ; Pan, Junlu ; Liu, Yuying ; Feng, Yuxin ; Li, Xiaoyu ; Zhang, Hanwen ; Zhu, Xudong ; Bai, Hui ; Yang, Qing ; Ben, Jingjing ; Chen, Qi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.4365-20, Article 4365
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Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons
Author / Creator:Chandrasekaran, Krish ; Choi, Joungil ; Arvas, Muhammed Ikbal ; Salimian, Mohammad ; Singh, Sujal ; Xu, Su ; Gullapalli, Rao P ; Kristian, Tibor ; Russell, James William
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2020-05, Vol.21 (11), p.3756
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The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives
Author / Creator:Zhang, Rui ; Shi, Shaoqing
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2023-03, Vol.29 (1), p.34-34, Article 34
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ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis
Author / Creator:He, Jiancheng ; Yi, Jianfeng ; Ji, Li ; Dai, Lingchen ; Chen, Yu ; Xue, Wanjiang
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2024-05, Vol.30 (1), p.69-69, Article 69
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NEDD4L mediates intestinal epithelial cell ferroptosis to restrict inflammatory bowel diseases and colorectal tumorigenesis
Author / Creator:Liang, Jingjing ; Wang, Ning ; Yao, Yihan ; Wang, Yingmei ; An, Xiang ; Wang, Haofei ; Liu, Huan ; Jiang, Yu ; Li, Hui ; Cheng, Xiaoqing ; Xu, Jiaqi ; Liang, Xiaojing ; Lou, Jun ; Xin, Zengfeng ; Zhang, Ting ; Wang, Xiaojian ; Lin, Wenlong
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2025-02, Vol.135 (3), p.1-21
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The Roles of NEDD4 Subfamily of HECT E3 Ubiquitin Ligases in Neurodevelopment and Neurodegeneration
Author / Creator:Haouari, Shanez ; Vourc’h, Patrick ; Jeanne, Médéric ; Marouillat, Sylviane ; Veyrat-Durebex, Charlotte ; Lanznaster, Débora ; Laumonnier, Frédéric ; Corcia, Philippe ; Blasco, Hélène ; Andres, Christian R.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-03, Vol.23 (7), p.3882
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The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells
Author / Creator:Shao, Genbao ; Wang, Ranran ; Sun, Aiqin ; Wei, Jing ; Peng, Ke ; Dai, Qian ; Yang, Wannian ; Lin, Qiong
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2018-02, Vol.17 (1), p.24-24, Article 24
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The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L
Author / Creator:Guarnieri, A. L. ; Towers, C. G. ; Drasin, D. J. ; Oliphant, M. U. J. ; Andrysik, Z. ; Hotz, T. J. ; Vartuli, R. L. ; Linklater, E. S. ; Pandey, A. ; Khanal, S. ; Espinosa, J. M. ; Ford, H. L.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2018-07, Vol.37 (28), p.3879-3893
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Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease
Author / Creator:Han, Fei ; Wu, Shi ; Dong, Ya ; Liu, Yanjie ; Sun, Bei ; Chen, Liming
Publisher:England: BioMed Central
Journal title:Journal of translational medicine, 2024-05, Vol.22 (1), p.465-14, Article 465
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IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway
Author / Creator:Chen, Ku-Chung ; Chen, Peng-Hsu ; Ho, Kuo-Hao ; Shih, Chwen-Ming ; Chou, Chih-Ming ; Cheng, Chia-Hsiung ; Lee, Chin-Cheng
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-12, Vol.14 (12), p.e0225913-e0225913
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Development and validation of AI/ML derived splice-switching oligonucleotides
Author / Creator:Fronk, Alyssa D ; Manzanares, Miguel A ; Zheng, Paulina ; Geier, Adam ; Anderson, Kendall ; Stanton, Shaleigh ; Zumrut, Hasan ; Gera, Sakshi ; Munch, Robin ; Frederick, Vanessa ; Dhingra, Priyanka ; Arun, Gayatri ; Akerman, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2024-06, Vol.20 (6), p.676-701
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The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy
Author / Creator:Kefalas, G. ; Priya, A. ; Astori, A. ; Persaud, A. ; Jing, L. ; Sydor, A. M. ; Yao, H. H. Y. ; Warner, N. ; Zhang, Y. ; Brumell, J. H. ; Muise, A. M. ; Sari, S. ; Su, H. C. ; Lenardo, M. J. ; Kahr, W. H. A. ; Raught, B. ; Rotin, D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.2682-13, Article 2682
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Long-read sequencing identifies the pathogenic nucleotide repeat expansion in RFC1 in a Japanese case of CANVAS
Author / Creator:Nakamura, Haruko ; Doi, Hiroshi ; Mitsuhashi, Satomi ; Miyatake, Satoko ; Katoh, Kazutaka ; Frith, Martin C. ; Asano, Tetsuya ; Kudo, Yosuke ; Ikeda, Takuya ; Kubota, Shun ; Kunii, Misako ; Kitazawa, Yu ; Tada, Mikiko ; Okamoto, Mitsuo ; Joki, Hideto ; Takeuchi, Hideyuki ; Matsumoto, Naomichi ; Tanaka, Fumiaki
Publisher:England: Nature Publishing Group
Journal title:Journal of human genetics, 2020-05, Vol.65 (5), p.475-480
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Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn’s disease by bioinformatics analysis and machine learning
Author / Creator:Chen, Wei ; Xu, Zeyan ; Sun, Haitao ; Feng, Wen ; Huang, Zhenhua
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2025-01, Vol.15 (1), p.3444-11, Article 3444
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Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells
Author / Creator:Wang, Xue ; Deng, Jiaojiao ; Yuan, Jinxia ; Tang, Xin ; Wang, Yuelong ; Chen, Haifeng ; Liu, Yi ; Zhou, Liangxue
Publisher:Athens: D.A. Spandidos
Journal title:International journal of oncology, 2017-08, Vol.51 (2), p.467-477
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Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline
Author / Creator:Sullivan, Kelly G ; Bashaw, Greg J
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2025-05, Vol.13
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Inhibition of HECT E3 ligases as potential therapy for COVID-19
Author / Creator:Novelli, Giuseppe ; Liu, Jing ; Biancolella, Michela ; Alonzi, Tonino ; Novelli, Antonio ; Patten, J. J. ; Cocciadiferro, Dario ; Agolini, Emanuele ; Colona, Vito Luigi ; Rizzacasa, Barbara ; Giannini, Rosalinda ; Bigio, Benedetta ; Goletti, Delia ; Capobianchi, Maria Rosaria ; Grelli, Sandro ; Mann, Justin ; McKee, Trevor D. ; Cheng, Ke ; Amanat, Fatima ; Krammer, Florian ; Guarracino, Andrea ; Pepe, Gerardo ; Tomino, Carlo ; Tandjaoui-Lambiotte, Yacine ; Uzunhan, Yurdagul ; Tubiana, Sarah ; Ghosn, Jade ; Notarangelo, Luigi D. ; Su, Helen C. ; Abel, Laurent ; Cobat, Aurélie ; Elhanan, Gai ; Grzymski, Joseph J. ; Latini, Andrea ; Sidhu, Sachdev S. ; Jain, Suresh ; Davey, Robert A. ; Casanova, Jean-Laurent ; Wei, Wenyi ; Pandolfi, Pier Paolo
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-03, Vol.12 (4), p.310-310, Article 310
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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation
Author / Creator:Liu, Qingjun ; Zhang, Shihui ; Sun, Zhongjie ; Guo, Xiao ; Zhou, Hong
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-11, Vol.26 (11), p.2386-2399
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NEDD4 expression is associated with breast cancer progression and is predictive of a poor prognosis
Author / Creator:Wan, Lingfeng ; Liu, Tao ; Hong, Zhipeng ; Pan, You ; Sizemore, Steven T. ; Zhang, Junran ; Ma, Zhefu
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2019-12, Vol.21 (1), p.148-148, Article 148
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The Ubiquitin Ligase Adaptor NDFIP1 Interacts with TRESK and Negatively Regulates the Background K+ Current
Author / Creator:Pergel, Enikő ; Tóth, Dániel J. ; Baukál, Dóra ; Veres, Irén ; Czirják, Gábor
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.8879
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Showing 21 to 40 of 83 results

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Endothelial major vault protein alleviates vascular remodeling via promoting Parkin-mediated mitophagy

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Nicotinamide Mononucleotide Administration Prevents Experimental Diabetes-Induced Cognitive Impairment and Loss of Hippocampal Neurons

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The role of NEDD4 related HECT-type E3 ubiquitin ligases in defective autophagy in cancer cells: molecular mechanisms and therapeutic perspectives

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ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis

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NEDD4L mediates intestinal epithelial cell ferroptosis to restrict inflammatory bowel diseases and colorectal tumorigenesis

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The Roles of NEDD4 Subfamily of HECT E3 Ubiquitin Ligases in Neurodevelopment and Neurodegeneration

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The E3 ubiquitin ligase NEDD4 mediates cell migration signaling of EGFR in lung cancer cells

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The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L

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Aberrant expression of NEDD4L disrupts mitochondrial homeostasis by downregulating CaMKKβ in diabetic kidney disease

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IGF-1-enhanced miR-513a-5p signaling desensitizes glioma cells to temozolomide by targeting the NEDD4L-inhibited Wnt/β-catenin pathway

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Development and validation of AI/ML derived splice-switching oligonucleotides

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The primate-specific Nedd4-1(NE) localizes to late endosomes in response to amino acids to suppress autophagy

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Long-read sequencing identifies the pathogenic nucleotide repeat expansion in RFC1 in a Japanese case of CANVAS

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Identification of ubiquitination-related key biomarkers and immune infiltration in Crohn’s disease by bioinformatics analysis and machine learning

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Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells

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Commissureless acts as a substrate adapter in a conserved Nedd4 E3 ubiquitin ligase pathway to promote axon growth across the midline

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Inhibition of HECT E3 ligases as potential therapy for COVID-19

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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation

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NEDD4 expression is associated with breast cancer progression and is predictive of a poor prognosis

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The Ubiquitin Ligase Adaptor NDFIP1 Interacts with TRESK and Negatively Regulates the Background K+ Current

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