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Select record 21
ArticlesPeer ReviewedFull Text
A serine/threonine kinase gene defective in Peutz–Jeghers syndrome
Author / Creator:Hemminki, Akseli ; Markie, David ; Tomlinson, Ian ; Avizienyte, Egle ; Roth, Stina ; Loukola, Anu ; Bignell, Graham ; Warren, William ; Aminoff, Maria ; Höglund, Pia ; Järvinen, Heikki ; Kristo, Paula ; Pelin, Katarina ; Ridanpää, Maaret ; Salovaara, Reijo ; Toro, Tumi ; Bodmer, Walter ; Olschwang, Sylviane ; Olsen, Anne S. ; Stratton, Michael R. ; de la Chapelle, Albert ; Aaltonen, Lauri A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 1998-01, Vol.391 (6663), p.184-187
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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers
Author / Creator:Zhou, Xiao-Ping ; Loukola, Anu ; Salovaara, Reijo ; Nystrom-Lahti, Minna ; Peltomäki, Päivi ; de la Chapelle, Albert ; Aaltonen, Lauri A. ; Eng, Charis
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2002-08, Vol.161 (2), p.439-447
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Familial Cutaneous Leiomyomatosis Is a Two-Hit Condition Associated with Renal Cell Cancer of Characteristic Histopathology
Author / Creator:Kiuru, Maija ; Launonen, Virpi ; Hietala, Marja ; Aittomäki, Kristiina ; Vierimaa, Outi ; Salovaara, Reijo ; Arola, Johanna ; Pukkala, Eero ; Sistonen, Pertti ; Herva, Riitta ; Aaltonen, Lauri A.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2001-09, Vol.159 (3), p.825-829
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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers
Author / Creator:Kuismanen, Shannon A. ; Holmberg, Mari T. ; Salovaara, Reijo ; de la Chapelle, Albert ; Peltomäki, Päivi
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2000-05, Vol.156 (5), p.1773-1779
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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability
Author / Creator:Kuismanen, Shannon A. ; Moisio, Anu-Liisa ; Schweizer, Pascal ; Truninger, Kaspar ; Salovaara, Reijo ; Arola, Johanna ; Butzow, Ralf ; Jiricny, Josef ; Nyström-Lahti, Minna ; Peltomäki, Päivi
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2002-06, Vol.160 (6), p.1953-1958
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Induction of Cyclooxygenase-2 in a Mouse Model of Peutz-Jeghers Polyposis
Author / Creator:Rossi, Derrick J. ; Ylikorkala, Antti ; Korsisaari, Nina ; Salovaara, Reijo ; Luukko, Keijo ; Launonen, Virpi ; Henkemeyer, Mark ; Ristimäki, Ari ; Aaltonen, Lauri A. ; Mäkelä, Tomi P.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12327-12332
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Select record 27
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Genetic Reconstruction of Individual Colorectal Tumor Histories
Author / Creator:Tsao, Jen-Lan ; Yatabe, Yasushi ; Salovaara, Reijo ; Jarvinen, Heikki J. ; Mecklin, Jukka-Pekka ; Aaltonen, Lauri A. ; Tavare, Simon ; Shibata, Darryl
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2000-02, Vol.97 (3), p.1236-1241
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Select record 28
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Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers
Author / Creator:Kuismanen, Shannon A. ; Holmberg, Mari T. ; Salovaara, Reijo ; Schweizer, Pascal ; Aaltonen, Lauri A. ; de la Chapelle, Albert ; Nyström-Lahti, Minna ; Peltomäki, Päivi
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1999-10, Vol.96 (22), p.12661-12666
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Select record 29
ArticlesPeer ReviewedFull Text
LKB1 Somatic Mutations in Sporadic Tumors
Author / Creator:Avizienyte, Egle ; Loukola, Anu ; Roth, Stina ; Hemminki, Akseli ; Tarkkanen, Maija ; Salovaara, Reijo ; Arola, Johanna ; Bützow, Ralf ; Husgafvel-Pursiainen, Kirsti ; Kokkola, Arto ; Järvinen, Heikki ; Aaltonen, Lauri A.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 1999-03, Vol.154 (3), p.677-681
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Select record 30
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Allelic Analysis of Serous Ovarian Carcinoma Reveals Two Putative Tumor Suppressor Loci at 18q22-q23 Distal to SMAD4, SMAD2, and DCC
Author / Creator:Lassus, Heini ; Salovaara, Reijo ; Aaltonen, Lauri A. ; Butzow, Ralf
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 2001-07, Vol.159 (1), p.35-42
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Select record 31
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Microsatellite Instability in Adenomas as a Marker for Hereditary Nonpolyposis Colorectal Cancer
Author / Creator:Loukola, Anu ; Salovaara, Reijo ; Kristo, Paula ; Moisio, Anu-Liisa ; Kääriäinen, Helena ; Ahtola, Heikki ; Eskelinen, Matti ; Härkönen, Niilo ; Julkunen, Risto ; Kangas, Eero ; Ojala, Seppo ; Tulikoura, Jukka ; Valkamo, Erkki ; Järvinen, Heikki ; Mecklin, Jukka-Pekka ; de la Chapelle, Albert ; Aaltonen, Lauri A.
Publisher:Bethesda, MD: Elsevier Inc
Journal title:The American journal of pathology, 1999-12, Vol.155 (6), p.1849-1853
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Select record 32
ArticlesPeer ReviewedFull Text
Somatic microsatellite mutations as molecular tumor clocks
Author / Creator:Shibata, Darryl ; Navidi, William ; Salovaara, Reijo ; Li, Zhi-Hua ; Aaltonen, Lauri A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 1996-06, Vol.2 (6), p.676-681
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Select record 33
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Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis
Author / Creator:Laiho, P ; Kokko, A ; Vanharanta, S ; Salovaara, R ; Sammalkorpi, H ; Jaervinen, H ; Mecklin, J-P ; Karttunen, T J ; Tuppurainen, K ; Davalos, V ; Schwartz Jr, S ; Arango, D ; Maekinen, M J ; Aaltonen, L A
Journal title:Oncogene, 2007-01, Vol.26 (2), p.312-320
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Select record 34
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Comprehensive Analysis of SMAD4 Mutations and Protein Expression in Juvenile Polyposis : Evidence for a Distinct Genetic Pathway and Polyp Morphology in SMAD4 Mutation Carriers
Author / Creator:Woodford-Richens, Kelly L ; Rowan, Andrew J ; Poulsom, Richard ; Bevan, Stephen ; Salovaara, Reijo ; Aaltonen, Lauri A ; Houlston, Richard S ; Wright, Nicholas A ; Tomlinson, Ian P. M
Publisher:Bethesda, MD: ASIP
Journal title:The American journal of pathology, 2001-10, Vol.159 (4), p.1293-1300
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Select record 35
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Colorectal Adenoma and Cancer Divergence : Evidence of Multilineage Progression
Author / Creator:Tsao, Jen-Lan ; Tavare, Simon ; Salovaara, Reijo ; Jass, Jeremy R ; Aaltonen, Lauri A ; Shibata, Darryl
Publisher:Bethesda, MD: ASIP
Journal title:The American journal of pathology, 1999-06, Vol.154 (6), p.1815-1824
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Select record 36
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PolyA Deletions in Hereditary Nonpolyposis Colorectal Cancer : Mutations Before a Gatekeeper
Author / Creator:Kim, Kyoung-Mee ; Salovaara, Reijo ; Mecklin, Jukka-Pekka ; Jarvinen, Heikki J ; Aaltonen, Lauri A ; Shibata, Darryl
Publisher:Bethesda, MD: ASIP
Journal title:The American journal of pathology, 2002-04, Vol.160 (4), p.1503-1506
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Select record 37
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Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases
Author / Creator:Laiho, Päivi ; Hienonen, Tuija ; Karhu, Auli ; Lipton, Lara ; Aalto, Yan ; Thomas, Huw JW ; Birkenkamp-Demtroder, Karin ; Hodgson, Shirley ; Salovaara, Reijo ; Mecklin, Jukka-Pekka ; Järvinen, Heikki ; Knuutila, Sakari ; Halford, Sarah ; Ørntoft, Torben F ; Tomlinson, Ian ; Launonen, Virpi ; Houlston, Richard ; Aaltonen, Lauri A
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2003-04, Vol.22 (14), p.2206-2214
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Select record 38
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Genetic and epigenetic modification of MLH1 / Reply
Author / Creator:Perucho, Manuel ; Peltomaki, Paivi ; de la Chapelle, Albert ; Kuismanen, Shannon A
Publisher:Hagerstown: American Society for Investigative Pathology
Journal title:The American journal of pathology, 2000-09, Vol.157 (3), p.1052
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Select record 39
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Tracing Cell Fates in Human Colorectal Tumors from Somatic Microsatellite Mutations : Evidence of Adenomas with Stem Cell Architecture
Author / Creator:Tsao, Jen-Lan ; Zhang, Jingsong ; Salovaara, Reijo ; Li, Zhi-Hua ; Jarvinen, Heikki J ; Mecklin, Jukka-Pekka ; Aaltonen, Lauri A ; Shibata, Darryl
Publisher:United States: ASIP
Journal title:The American journal of pathology, 1998-10, Vol.153 (4), p.1189-1200
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Select record 40
ArticlesPeer ReviewedFull Text
Intestinal cancer in patients with a germline mutation in the down-regulated in adenoma (DRA) gene
Author / Creator:Hemminki, Akseli ; Höglund, Pia ; Pukkala, Eero ; Salovaara, Reijo ; Järvinen, Heikki ; Norio, Reijo ; Aaltonen, Lauri A
Publisher:Basingstoke: Nature Publishing
Journal title:Oncogene, 1998-02, Vol.16 (5), p.681-684
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Showing 21 to 40 of 36 results

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A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

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PTEN Mutational Spectra, Expression Levels, and Subcellular Localization in Microsatellite Stable and Unstable Colorectal Cancers

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Familial Cutaneous Leiomyomatosis Is a Two-Hit Condition Associated with Renal Cell Cancer of Characteristic Histopathology

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Genetic and Epigenetic Modification of MLH1 Accounts for a Major Share of Microsatellite-Unstable Colorectal Cancers

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Endometrial and Colorectal Tumors from Patients with Hereditary Nonpolyposis Colon Cancer Display Different Patterns of Microsatellite Instability

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Induction of Cyclooxygenase-2 in a Mouse Model of Peutz-Jeghers Polyposis

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Genetic Reconstruction of Individual Colorectal Tumor Histories

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Epigenetic Phenotypes Distinguish Microsatellite-Stable and -Unstable Colorectal Cancers

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LKB1 Somatic Mutations in Sporadic Tumors

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Allelic Analysis of Serous Ovarian Carcinoma Reveals Two Putative Tumor Suppressor Loci at 18q22-q23 Distal to SMAD4, SMAD2, and DCC

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Microsatellite Instability in Adenomas as a Marker for Hereditary Nonpolyposis Colorectal Cancer

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Somatic microsatellite mutations as molecular tumor clocks

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Serrated carcinomas form a subclass of colorectal cancer with distinct molecular basis

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Comprehensive Analysis of SMAD4 Mutations and Protein Expression in Juvenile Polyposis : Evidence for a Distinct Genetic Pathway and Polyp Morphology in SMAD4 Mutation Carriers

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Colorectal Adenoma and Cancer Divergence : Evidence of Multilineage Progression

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PolyA Deletions in Hereditary Nonpolyposis Colorectal Cancer : Mutations Before a Gatekeeper

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Genome-wide allelotyping of 104 Finnish colorectal cancers reveals an excess of allelic imbalance in chromosome 20q in familial cases

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Genetic and epigenetic modification of MLH1 / Reply

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Tracing Cell Fates in Human Colorectal Tumors from Somatic Microsatellite Mutations : Evidence of Adenomas with Stem Cell Architecture

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Intestinal cancer in patients with a germline mutation in the down-regulated in adenoma (DRA) gene

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