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Select record 21
ArticlesPeer ReviewedFull Text
Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study
Author / Creator:Wilson, Julie K ; Zhao, Yuan ; Singer, Mervyn ; Spencer, Jo ; Shankar-Hari, Manu
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2018-04, Vol.22 (1), p.95-95, Article 95
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ArticlesPeer ReviewedFull Text
The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?
Author / Creator:Tatham, Kate C. ; Shankar-Hari, Manu ; Arabi, Yaseen M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2021-11, Vol.47 (11), p.1315-1318
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COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland
Author / Creator:Richards-Belle, Alvin ; Orzechowska, Izabella ; Gould, Doug W. ; Thomas, Karen ; Doidge, James C. ; Mouncey, Paul R. ; Christian, Michael D. ; Shankar-Hari, Manu ; Harrison, David A. ; Rowan, Kathryn M.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-11, Vol.46 (11), p.2035-2047
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ArticlesPeer ReviewedFull Text
Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?
Author / Creator:Shankar-Hari, Manu ; Fish, Matthew ; Azoulay, Elie
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-01, Vol.46 (1), p.119-121
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Physiological dead space ventilation, disease severity and outcome in ventilated patients with hypoxaemic respiratory failure due to coronavirus disease 2019
Author / Creator:Vasques, Francesco ; Sanderson, Barnaby ; Formenti, Federico ; Shankar-Hari, Manu ; Camporota, Luigi
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-11, Vol.46 (11), p.2092-2093
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Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies
Author / Creator:Shankar-Hari, Manu ; Ambler, Michael ; Mahalingasivam, Viyaasan ; Jones, Andrew ; Rowan, Kathryn ; Rubenfeld, Gordon D
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2016-04, Vol.20 (1), p.101-101, Article 101
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Trials on oxygen supplementation in sepsis: better late than never
Author / Creator:Perner, Anders ; De Jong, Audrey ; Shankar-Hari, Manu
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-01, Vol.46 (1), p.116-118
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Could stress ulcer prophylaxis increase mortality in high-acuity patients?
Author / Creator:Harhay, Michael O. ; Young, Paul J. ; Shankar-Hari, Manu
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Intensive care medicine, 2020-04, Vol.46 (4), p.793-795
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International variation in the management of severe COVID-19 patients
Author / Creator:Azoulay, Elie ; de Waele, Jan ; Ferrer, Ricard ; Staudinger, Thomas ; Borkowska, Marta ; Povoa, Pedro ; Iliopoulou, Katerina ; Artigas, Antonio ; Schaller, Stefan J ; Shankar-Hari, Manu ; Pellegrini, Mariangela ; Darmon, Michael ; Kesecioglu, Jozef ; Cecconi, Maurizio
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2020-08, Vol.24 (1), p.486-486, Article 486
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Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials
Author / Creator:Santhakumaran, Shalini ; Gordon, Anthony ; Prevost, A Toby ; O'Kane, Cecilia ; McAuley, Daniel F ; Shankar-Hari, Manu
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2019-05, Vol.23 (1), p.156-156, Article 156
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Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial
Author / Creator:Boyle, Andrew James ; Ferris, Peter ; Bradbury, Ian ; Conlon, John ; Shankar-Hari, Manu ; Rogers, Angela J ; O'Kane, Cecilia M ; McAuley, Daniel F
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2022-06, Vol.26 (1), p.164-164, Article 164
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Select record 32
ArticlesPeer ReviewedFull Text
Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia
Author / Creator:Blette, Bryan S. ; Granholm, Anders ; Li, Fan ; Shankar-Hari, Manu ; Lange, Theis ; Munch, Marie Warrer ; Møller, Morten Hylander ; Perner, Anders ; Harhay, Michael O.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-04, Vol.13 (1), p.6570-6570, Article 6570
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Select record 33
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The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database
Author / Creator:McGuigan, Peter J ; Giallongo, Elisa ; Blackwood, Bronagh ; Doidge, James ; Harrison, David A ; Nichol, Alistair D ; Rowan, Kathryn M ; Shankar-Hari, Manu ; Skrifvars, Markus B ; Thomas, Karen ; McAuley, Danny F
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2023-01, Vol.27 (1), p.4-4, Article 4
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Select record 34
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Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials
Author / Creator:Shankar-Hari, Manu ; Estcourt, Lise ; Harvala, Heli ; Roberts, David ; Menon, David K
Publisher:London: BioMed Central Ltd
Journal title:Critical care (London, England), 2020-07, Vol.24 (1), p.1-449, Article 449
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Select record 35
ArticlesPeer ReviewedFull Text
Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective
Author / Creator:Shankar-Hari, Manu ; Spencer, Jo ; Sewell, William A ; Rowan, Kathryn M ; Singer, Mervyn
Publisher:England: BioMed Central
Journal title:Critical care (London, England), 2012-12, Vol.16 (2), p.206-206
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Association between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis
Author / Creator:Godolphin, Peter J ; Fisher, David J ; Berry, Lindsay R ; Derde, Lennie P G ; Diaz, Janet V ; Gordon, Anthony C ; Lorenzi, Elizabeth ; Marshall, John C ; Murthy, Srinivas ; Shankar-Hari, Manu ; Sterne, Jonathan A C ; Tierney, Jayne F ; Vale, Claire L
Publisher:United States: Public Library of Science
Journal title:PloS one, 2022-07, Vol.17 (7), p.e0270668
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Select record 37
ArticlesPeer ReviewedFull Text
The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study
Author / Creator:McGuigan, Peter J ; Shankar-Hari, Manu ; Harrison, David A ; Laffey, John G ; McAuley, Danny F
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2020-06, Vol.24 (1), p.336-336, Article 336
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Select record 38
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Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release
Author / Creator:Morad, Hassan O. J. ; Luqman, Suaib ; Pinto, Larissa Garcia ; Cunningham, Kevin P. ; Vilar, Bruno ; Clayton, Georgia ; Shankar-Hari, Manu ; McNaughton, Peter A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-06, Vol.12 (1), p.11078-11078, Article 11078
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Select record 39
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Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern
Author / Creator:Dupont, Liane ; Snell, Luke B. ; Graham, Carl ; Seow, Jeffrey ; Merrick, Blair ; Lechmere, Thomas ; Maguire, Thomas J. A. ; Hallett, Sadie R. ; Pickering, Suzanne ; Charalampous, Themoula ; Alcolea-Medina, Adela ; Huettner, Isabella ; Jimenez-Guardeño, Jose M. ; Acors, Sam ; Almeida, Nathalia ; Cox, Daniel ; Dickenson, Ruth E. ; Galao, Rui Pedro ; Kouphou, Neophytos ; Lista, Marie Jose ; Ortega-Prieto, Ana Maria ; Wilson, Harry ; Winstone, Helena ; Fairhead, Cassandra ; Su, Jia Zhe ; Nebbia, Gaia ; Batra, Rahul ; Neil, Stuart ; Shankar-Hari, Manu ; Edgeworth, Jonathan D. ; Malim, Michael H. ; Doores, Katie J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature microbiology, 2021-11, Vol.6 (11), p.1433-1442
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Select record 40
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ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A...
Author / Creator:Wilkinson, Tom ; Dixon, Rupert ; Page, Clive ; Carroll, Miles ; Griffiths, Gareth ; Ho, Ling-Pei ; De Soyza, Anthony ; Felton, Timothy ; Lewis, Keir E ; Phekoo, Karen ; Chalmers, James D ; Gordon, Anthony ; McGarvey, Lorcan ; Doherty, Jillian ; Read, Robert C ; Shankar-Hari, Manu ; Martinez-Alier, Nuria ; O'Kelly, Michael ; Duncan, Graeme ; Walles, Roelize ; Sykes, James ; Summers, Charlotte ; Singh, Dave
Publisher:England: BioMed Central Ltd
Journal title:Current controlled trials in cardiovascular medicine, 2020-07, Vol.21 (1), p.691-3, Article 691
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Lymphocyte subset expression and serum concentrations of PD-1/PD-L1 in sepsis - pilot study

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The REMDACTA trial: do interleukin receptor antagonists provide additional benefit in COVID-19?

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COVID-19 in critical care: epidemiology of the first epidemic wave across England, Wales and Northern Ireland

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Should we consider blocking the inhibitory immune checkpoint molecules for treating T cell exhaustion in sepsis?

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Physiological dead space ventilation, disease severity and outcome in ventilated patients with hypoxaemic respiratory failure due to coronavirus disease 2019

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Evidence for a causal link between sepsis and long-term mortality: a systematic review of epidemiologic studies

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Trials on oxygen supplementation in sepsis: better late than never

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Could stress ulcer prophylaxis increase mortality in high-acuity patients?

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International variation in the management of severe COVID-19 patients

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Heterogeneity of treatment effect by baseline risk of mortality in critically ill patients: re-analysis of three recent sepsis and ARDS randomised controlled trials

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Baseline plasma IL-18 may predict simvastatin treatment response in patients with ARDS: a secondary analysis of the HARP-2 randomised clinical trial

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Causal Bayesian machine learning to assess treatment effect heterogeneity by dexamethasone dose for patients with COVID-19 and severe hypoxemia

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The effect of blood pressure on mortality following out-of-hospital cardiac arrest: a retrospective cohort study of the United Kingdom Intensive Care National Audit and Research Centre database

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Convalescent plasma to treat critically ill patients with COVID-19: framing the need for randomised clinical trials

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Bench-to-bedside review: Immunoglobulin therapy for sepsis - biological plausibility from a critical care perspective

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Association between tocilizumab, sarilumab and all-cause mortality at 28 days in hospitalised patients with COVID-19: A network meta-analysis

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The interaction between arterial oxygenation and carbon dioxide and hospital mortality following out of hospital cardiac arrest: a cohort study

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Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release

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Neutralizing antibody activity in convalescent sera from infection in humans with SARS-CoV-2 and variants of concern

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ACCORD: A Multicentre, Seamless, Phase 2 Adaptive Randomisation Platform Study to Assess the Efficacy and Safety of Multiple Candidate Agents for the Treatment of COVID-19 in Hospitalised Patients: A...

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