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ArticlesPeer ReviewedFull Text
High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs
Author / Creator:Zhu, Junbo ; Duan, Yabin ; Duo, Delong ; Yang, Jianxin ; Bai, Xue ; Liu, Guiqin ; Wang, Qian ; Wang, Xuejun ; Qu, Ning ; Zhou, Yang ; Li, Xiangyang
Publisher:Basel: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2022-10, Vol.15 (10), p.1303
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A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice
Author / Creator:Mimche, Sylvie M. ; Lee, Choon-myung ; Liu, Ken H. ; Mimche, Patrice N. ; Harvey, R. Donald ; Murphy, Thomas J. ; Nyagode, Beatrice A. ; Jones, Dean P. ; Lamb, Tracey J. ; Morgan, Edward T.
Publisher:England: BioMed Central Ltd
Journal title:Malaria journal, 2019-07, Vol.18 (1), p.234-16, Article 234
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Twelve-Month Frequency of Drug-Metabolizing Enzyme and Transporter-Based Drug-Drug Interaction Potential in Patients Receiving Oral Enzyme-Targeted Kinase Inhibitor Antineoplastic Agents
Author / Creator:Bowlin, Steven J., DO, MPH, PhD ; Xia, Fang, PhD ; Wang, Wenyi, MS ; Robinson, Keisha D., MBA, MPM ; Stanek, Eric J., PharmD
Publisher:England: Elsevier Inc
Journal title:Mayo Clinic proceedings, 2013-02, Vol.88 (2), p.139-148
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Impact of quercetin-induced changes in drug-metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats
Author / Creator:Liu, Yani ; Luo, Xiaomei ; Yang, Chunxiao ; Yang, Tingyu ; Zhou, Jiali ; Shi, Shaojun
Publisher:Greece: D.A. Spandidos
Journal title:Molecular medicine reports, 2016-10, Vol.14 (4), p.3073-3085
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ArticlesPeer ReviewedFull Text
Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications
Author / Creator:Zhu, Hanhan ; Liu, Guangming ; Chang, Qi ; Yan, Mengyao ; Yang, Kun ; Li, Yanxin ; Nie, Yali ; Li, Xiaotian ; Han, Shengna ; Wang, Pei ; Zhang, Lirong
Publisher:Switzerland: MDPI AG
Journal title:Toxics (Basel), 2023-01, Vol.11 (1), p.82
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Generalized Multifactor Dimensionality Reduction (GMDR) Analysis of Drug-Metabolizing Enzyme-Encoding Gene Polymorphisms may Predict Treatment Outcomes in Indian Breast Cancer Patients
Author / Creator:Agarwal, Gaurav ; Tulsyan, Sonam ; Lal, Punita ; Mittal, Balraj
Publisher:Cham: Springer International Publishing
Journal title:World journal of surgery, 2016-07, Vol.40 (7), p.1600-1610
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ArticlesPeer ReviewedFull Text
Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia
Author / Creator:Vanwong, Natchaya ; Tipnoppanon, Sayanit ; Na Nakorn, Chalitpon ; Srisawasdi, Pornpen ; Rodcharoen, Punyanuch ; Medhasi, Sadeep ; Chariyavilaskul, Pajaree ; Siwamogsatham, Sarawut ; Vorasettakarnkij, Yongkasem ; Sukasem, Chonlaphat
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Pharmacogenomics and personalized medicine, 2022-01, Vol.15, p.119-130
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ArticlesPeer ReviewedFull Text
Inter‐individual and inter‐regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 dono...
Author / Creator:Li, Albert P. ; Ho, Ming‐Chih D. ; Alam, Novera ; Mitchell, Walter ; Wong, Susan ; Yan, Zhengyin ; Kenny, Jane R. ; E. C. A. Hop, Cornelis
Publisher:United States: John Wiley & Sons, Inc
Journal title:Pharmacology research & perspectives, 2020-10, Vol.8 (5), p.e00645-n/a
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ArticlesFull Text
Expression of glutathione S-transferase A1, a phase II drug-metabolizing enzyme in acute hepatic injury on mice
Author / Creator:Ma, Xin ; Liu, Fangping ; Li, Minmin ; Li, Zhi ; Lin, Yuexia ; Li, Rui ; Li, Changwen ; Chang, Yicong ; Zhao, Changwei ; Han, Qing ; Zhou, Qiong ; Zhao, Yulin ; Wang, Dening ; Liu, Jingli
Publisher:Greece: Spandidos Publications UK Ltd
Journal title:Experimental and therapeutic medicine, 2017-10, Vol.14 (4), p.3798-3804
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ArticlesPeer ReviewedFull Text
Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory
Author / Creator:Shrestha, Binu ; Reed, J. Michael ; Starks, Philip T. ; Kaufman, Gretchen E. ; Goldstone, Jared V. ; Roelke, Melody E. ; O'Brien, Stephen J. ; Koepfli, Klaus-Peter ; Frank, Laurence G. ; Court, Michael H.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-03, Vol.6 (3), p.e18046
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ArticlesPeer ReviewedFull Text
Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan
Author / Creator:Ahmed, Sagheer ; Altaf, Nadeem ; Ejaz, Mahnoor ; Zulfiqar, Zaira ; Janjua, Kholood ; Festila, Dana ; Cristina, Nicula
Publisher:San Diego: PeerJ. Ltd
Journal title:PeerJ (San Francisco, CA), 2020-08, Vol.8, p.e9721-e9721, Article e9721
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ArticlesPeer ReviewedFull Text
Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis
Author / Creator:Fisher, Craig D ; Jackson, Jonathan P ; Lickteig, Andrew J ; Augustine, Lisa M ; Cherrington, Nathan J
Publisher:Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
Journal title:Archives of toxicology, 2008-12, Vol.82 (12), p.959-964
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ArticlesPeer ReviewedFull Text
Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherap...
Author / Creator:Kim, Kyu-pyo ; Ahn, Jin-Hee ; Kim, Sung-Bae ; Jung, Kyung Hae ; Yoon, Dok Hyun ; Lee, Jung Shin ; Ahn, Sei-Hyun
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2012-05, Vol.69 (5), p.1221-1227
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Select record 34
ArticlesPeer ReviewedFull Text
Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients
Author / Creator:Afsar, Nasir Ali ; Ufer, Mike ; Haenisch, Sierk ; Remmler, Cornelia ; Mateen, Ahmed ; Usman, Ahmed ; Ahmed, Khwaja Zafar ; Ahmad, Hakimuddin Razi ; Cascorbi, Ingolf
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:European journal of clinical pharmacology, 2012-04, Vol.68 (4), p.389-395
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ArticlesPeer ReviewedFull Text
Effect of a Triphasic Oral Contraceptive on Drug-Metabolizing Enzyme Activity as Measured by the Validated Cooperstown 5+1 Cocktail
Author / Creator:Shelepova, Tatiana ; Nafziger, Anne N. ; Victory, Jennifer ; Kashuba, Angela D. M. ; Rowland, Elizabeth ; Zhang, Yanhua ; Sellers, Edward ; Kearns, Gregory ; Leeder, J. Steven ; Gaedigk, Andrea ; Bertino Jr, Joseph S.
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of clinical pharmacology, 2005-12, Vol.45 (12), p.1413-1421
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Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance
Author / Creator:Wu, Alan H B
Publisher:England: BioMed Central Ltd
Journal title:Clinical proteomics, 2011-07, Vol.8 (1), p.12-12, Article 12
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Association of nasopharyngeal cancer risk with genetic polymorphisms of drug-metabolizing enzyme genes GSTM1, GSTT1 and CYP1A1 (rs4646903 variant), in tobacco addicted patients of Pashtun ethnicity of...
Author / Creator:Zakiullah, - ; Saeed, Muhammad ; Javed, Nabila ; Khuda, Fazli ; Ovais, Muhammad
Publisher:Pakistan
Journal title:Pakistan journal of pharmaceutical sciences, 2019-09, Vol.32 (5), p.2107
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Select record 38
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Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder
Author / Creator:Sukasem, Chonlaphat ; Medhasi, Sadeep ; Pasomsub, Ekawat ; Vanwong, Natchaya ; Ngamsamut, Nattawat ; Puangpetch, Apichaya ; Chamnanphon, Montri ; Hongkaew, Yaowaluck ; Limsila, Penkhae ; Pinthong, Darawan
Publisher:New Zealand: Dove Medical Press Limited
Journal title:Neuropsychiatric disease and treatment, 2016-01, Vol.12, p.843-851
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ArticlesPeer ReviewedFull Text
Association of nasopharyngeal cancer risk with genetic polymorphisms of drug-metabolizing enzyme genes GSTMly GSTT1 and CYP1A1 , in tobacco addicted patients of Pashtun ethnicity of Khyber Pakhtunkhwa...
Author / Creator:Zakiullah ; Saeed, Muhammad ; Javed, Nabila ; Khuda, Fazli ; Ovais, Muhammad
Publisher:Pakistan Journal of Pharmaceutical Sciences
Journal title:Pakistan journal of pharmaceutical sciences, 2019-09, Vol.32 (5), p.2107
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Nuclear Receptors and the Regulation of Drug-Metabolizing Enzymes and Drug Transporters: Implications for Interindividual Variability in Response to Drugs
Author / Creator:Urquhart, Bradley L. ; Tirona, Rommel G. ; Kim, Richard B.
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Journal of clinical pharmacology, 2007-05, Vol.47 (5), p.566-578
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Showing 21 to 40 of 2,452 results

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High-altitude Hypoxia Influences the Activities of the Drug-Metabolizing Enzyme CYP3A1 and the Pharmacokinetics of Four Cardiovascular System Drugs

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A non-lethal malarial infection results in reduced drug metabolizing enzyme expression and drug clearance in mice

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Twelve-Month Frequency of Drug-Metabolizing Enzyme and Transporter-Based Drug-Drug Interaction Potential in Patients Receiving Oral Enzyme-Targeted Kinase Inhibitor Antineoplastic Agents

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Impact of quercetin-induced changes in drug-metabolizing enzyme and transporter expression on the pharmacokinetics of cyclosporine in rats

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Prenatal Lipopolysaccharide Exposure Alters Hepatic Drug-Metabolizing Enzyme Expression in Mouse Offspring via Histone Modifications

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Generalized Multifactor Dimensionality Reduction (GMDR) Analysis of Drug-Metabolizing Enzyme-Encoding Gene Polymorphisms may Predict Treatment Outcomes in Indian Breast Cancer Patients

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Association of Drug-Metabolizing Enzyme and Transporter Gene Polymorphisms and Lipid-Lowering Response to Statins in Thai Patients with Dyslipidemia

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Inter‐individual and inter‐regional variations in enteric drug metabolizing enzyme activities: Results with cryopreserved human intestinal mucosal epithelia (CHIM) from the small intestines of 14 dono...

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Expression of glutathione S-transferase A1, a phase II drug-metabolizing enzyme in acute hepatic injury on mice

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Evolution of a Major Drug Metabolizing Enzyme Defect in the Domestic Cat and Other Felidae: Phylogenetic Timing and the Role of Hypercarnivory

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Genetic variations in the drug metabolizing enzyme, CYP2E1, among various ethnic populations of Pakistan

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Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis

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Prospective evaluation of the drug-metabolizing enzyme polymorphisms and toxicity profile of docetaxel in Korean patients with operable lymph node-positive breast cancer receiving adjuvant chemotherap...

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Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients

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Effect of a Triphasic Oral Contraceptive on Drug-Metabolizing Enzyme Activity as Measured by the Validated Cooperstown 5+1 Cocktail

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Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance

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Association of nasopharyngeal cancer risk with genetic polymorphisms of drug-metabolizing enzyme genes GSTM1, GSTT1 and CYP1A1 (rs4646903 variant), in tobacco addicted patients of Pashtun ethnicity of...

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Clinically relevant genetic variants of drug-metabolizing enzyme and transporter genes detected in Thai children and adolescents with autism spectrum disorder

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Association of nasopharyngeal cancer risk with genetic polymorphisms of drug-metabolizing enzyme genes GSTMly GSTT1 and CYP1A1 , in tobacco addicted patients of Pashtun ethnicity of Khyber Pakhtunkhwa...

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Nuclear Receptors and the Regulation of Drug-Metabolizing Enzymes and Drug Transporters: Implications for Interindividual Variability in Response to Drugs

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