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ArticlesPeer ReviewedFull Text
TZD-Based Hybrid Molecules Act as Dual Anti-Mycobacterium tuberculosis and Anti-Toxoplasma gondii Agents
Author / Creator:Dzitko, Katarzyna ; Kaproń, Barbara ; Paneth, Agata ; Bekier, Adrian ; Plech, Tomasz ; Paneth, Piotr ; Trotsko, Nazar
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-01, Vol.24 (3), p.2069
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Thymoquinone-protoflavone hybrid molecules as potential antitumor agents Thymoquinone-protoflavone hybrid molecules as potential antitumor agents
Author / Creator:Sara H. H. Ahmed ; Bizhar A. Tayeb ; Tímea Gonda ; Gábor Girst ; Kornél Szőri ; Róbert Berkecz ; István Zupkó ; Renáta Minorics ; Attila Hunyadi
Publisher:Public Library of Science (PLoS)
Journal title:PloS one, 2024-01, Vol.19 (1)
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Chlorambucil-Bearing Hybrid Molecules in the Development of Potential Anticancer Agents
Author / Creator:Peter, Sijongesonke ; Aderibigbe, Blessing Atim
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-09, Vol.28 (19), p.6889
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Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells
Author / Creator:Kim, Na Young ; Vishwanath, Divakar ; Xi, Zhang ; Nagaraja, Omantheswara ; Swamynayaka, Ananda ; Kumar Harish, Keshav ; Basappa, Shreeja ; Madegowda, Mahendra ; Pandey, Vijay ; Sethi, Gautam ; Lobie, Peter E. ; Ahn, Kwang Seok ; Basappa, Basappa
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2023-04, Vol.28 (8), p.3450
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Fungal laccases as tools for the synthesis of new hybrid molecules and biomaterials
Author / Creator:Mikolasch, Annett ; Schauer, Frieder
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Applied microbiology and biotechnology, 2009-03, Vol.82 (4), p.605-624
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New Synthetic Analogs of Natural 5Z,9Z-Dienoic Acids—Hybrid Molecules Based on Oleanolic Acid: Synthesis and Study of Antitumor Activity
Author / Creator:Tuktarova, Regina A. ; Dzhemileva, Lilya U. ; Dzhemilev, Usein M. ; D’yakonov, Vladimir A.
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2024-12, Vol.16 (23), p.3893
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Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules
Author / Creator:Defant, Andrea ; Mancini, Ines
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-06, Vol.24 (12), p.2224
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Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis
Author / Creator:Micheli, Laura ; Bozdag, Murat ; Akgul, Ozlem ; Carta, Fabrizio ; Guccione, Clizia ; Bergonzi, Maria Camilla ; Bilia, Anna Rita ; Cinci, Lorenzo ; Lucarini, Elena ; Parisio, Carmen ; Supuran, Claudiu T. ; Ghelardini, Carla ; Di Cesare Mannelli, Lorenzo
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-04, Vol.20 (8), p.1923
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ArticlesPeer ReviewedFull Text
Hybrid Molecules Consisting of Lysine Dendrons with Several Hydrophobic Tails: A SCF Study of Self-Assembling
Author / Creator:Shavykin, Oleg V. ; Mikhtaniuk, Sofia E. ; Fatullaev, Emil I. ; Neelov, Igor M. ; Leermakers, Frans A. M. ; Brito, Mariano E. ; Holm, Christian ; Borisov, Oleg V. ; Darinskii, Anatoly A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2023-01, Vol.24 (3), p.2078
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ArticlesPeer ReviewedFull Text
Synthesis and Anticancer Activity of Hybrid Molecules Based on Lithocholic and (5Z,9Z)-Tetradeca-5,9-dienedioic Acids Linked via Mono(di,tri,tetra)ethylene Glycol and α,ω-Diaminoalkane Units
Author / Creator:D’yakonov, Vladimir A. ; Tuktarova, Regina A. ; Dzhemileva, Lilya U. ; Ishmukhametova, Svetlana R. ; Dzhemilev, Usein M.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-01, Vol.14 (2), p.84
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ArticlesPeer ReviewedFull Text
Synthesis of Hybrid Molecules with Imidazole-1,3,4-thiadiazole Core and Evaluation of Biological Activity on Trypanosoma cruzi and Leishmania donovani
Author / Creator:Mijoba, Ali ; Parra-Giménez, Nereida ; Fernandez-Moreira, Esteban ; Ramírez, Hegira ; Serrano, Xenón ; Blanco, Zuleima ; Espinosa, Sandra ; Charris, Jaime E.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2024-08, Vol.29 (17), p.4125
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ArticlesPeer ReviewedFull Text
Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties
Author / Creator:Makowska, Anna ; Sączewski, Franciszek ; Bednarski, Patrick J. ; Sączewski, Jarosław ; Balewski, Łukasz
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-07, Vol.23 (7), p.1616
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ArticlesPeer ReviewedFull Text
Conjugation as a Tool in Therapeutics: Role of Amino Acids/Peptides-Bioactive (Including Heterocycles) Hybrid Molecules in Treating Infectious Diseases
Author / Creator:Gattu, Rohith ; Ramesh, Sanjay S. ; Nadigar, Siddaram ; D, Channe Gowda ; Ramesh, Suhas
Publisher:Switzerland: MDPI AG
Journal title:Antibiotics (Basel), 2023-03, Vol.12 (3), p.532
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ArticlesPeer ReviewedFull Text
Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases
Author / Creator:Załuski, Michał ; Karcz, Tadeusz ; Drabczyńska, Anna ; Vielmuth, Christin ; Olejarz-Maciej, Agnieszka ; Głuch-Lutwin, Monika ; Mordyl, Barbara ; Siwek, Agata ; Satała, Grzegorz ; Müller, Christa E. ; Kieć-Kononowicz, Katarzyna
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-07, Vol.13 (7), p.1079
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ArticlesPeer ReviewedFull Text
Molecular mechanisms of bifunctional vitamin D receptor agonist-histone deacetylase inhibitor hybrid molecules in triple-negative breast cancer
Author / Creator:Barbier, Camille ; Mansour, Ali ; Ismailova, Aiten ; Sarmadi, Fatemeh ; Scarlata, David A. ; Bouttier, Manuella ; Zeitouni, Camille ; Wang, Catherine ; Gleason, James L. ; White, John H.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-04, Vol.12 (1), p.6745-13, Article 6745
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ArticlesPeer ReviewedFull Text
Hybrid Molecules of Azithromycin with Chloramphenicol and Metronidazole: Synthesis and Study of Antibacterial Properties
Author / Creator:Volynkina, Inna A. ; Bychkova, Elena N. ; Karakchieva, Anastasiia O. ; Tikhomirov, Alexander S. ; Zatonsky, George V. ; Solovieva, Svetlana E. ; Martynov, Maksim M. ; Grammatikova, Natalia E. ; Tereshchenkov, Andrey G. ; Paleskava, Alena ; Konevega, Andrey L. ; Sergiev, Petr V. ; Dontsova, Olga A. ; Osterman, Ilya A. ; Shchekotikhin, Andrey E. ; Tevyashova, Anna N.
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2024-01, Vol.17 (2), p.187
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Atom-efficient synthesis of hybrid molecules combining fragments of triazolopyrimidines and 3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1H)-one through 1,2,3-triazole linker
Author / Creator:Savateev, Konstantin V. ; Slepukhin, Pavel A. ; Kotovskaya, Svetlana K. ; Charushin, Valery N. ; Rusinov, Vladimir L. ; Chupakhin, Oleg N.
Publisher:New York: Springer US
Journal title:Chemistry of heterocyclic compounds (New York, N.Y. 1965), 2021-02, Vol.57 (2), p.143-153
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Design and synthesis of some novel hybrid molecules based on 4-thiazolidinone bearing pyridine-pyrazole scaffolds: molecular docking and molecular dynamics simulations of its major constituent onto DN...
Author / Creator:Desai, Nisheeth C. ; Jadeja, Dharmpalsinh J. ; Jethawa, Aratiba M. ; Ahmad, Iqrar ; Patel, Harun ; Dave, B. P.
Publisher:Cham: Springer International Publishing
Journal title:Molecular diversity, 2024-04, Vol.28 (2), p.693-709
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Design, synthesis and biological evaluation of novel 1,2,3-triazolyl [beta]-hydroxy alkyl/carbazole hybrid molecules
Author / Creator:Rad, Mohammad Navid; Soltani ; Behrouz, Somayeh ; Behrouz, Marzieh ; Sami, Akram ; Mardkhoshnood, Mehdi ; Zarenezhad, Ali ; Zarenezhad, Elham
Publisher:Dordrecht: Springer Nature B.V
Journal title:Molecular diversity, 2016-08, Vol.20 (3), p.705
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Synthesis, molecular docking and anti-diabetic studies of novel benzimidazole-pyrazoline hybrid molecules
Author / Creator:Ibraheem, Farhat ; Ahmad, Matloob ; Ashfaq, Usman Ali ; Aslam, Sana ; Khan, Zulfiqar Ali ; Sultan, Sadia
Publisher:Pakistan Journal of Pharmaceutical Sciences
Journal title:Pakistan journal of pharmaceutical sciences, 2020-03, Vol.33 (2S), p.847-854
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TZD-Based Hybrid Molecules Act as Dual Anti-Mycobacterium tuberculosis and Anti-Toxoplasma gondii Agents

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Thymoquinone-protoflavone hybrid molecules as potential antitumor agents Thymoquinone-protoflavone hybrid molecules as potential antitumor agents

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Chlorambucil-Bearing Hybrid Molecules in the Development of Potential Anticancer Agents

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Discovery of Pyrimidine- and Coumarin-Linked Hybrid Molecules as Inducers of JNK Phosphorylation through ROS Generation in Breast Cancer Cells

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Fungal laccases as tools for the synthesis of new hybrid molecules and biomaterials

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New Synthetic Analogs of Natural 5Z,9Z-Dienoic Acids—Hybrid Molecules Based on Oleanolic Acid: Synthesis and Study of Antitumor Activity

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Design, Synthesis and Cancer Cell Growth Inhibition Evaluation of New Aminoquinone Hybrid Molecules

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Pain Relieving Effect of-NSAIDs-CAIs Hybrid Molecules: Systemic and Intra-Articular Treatments against Rheumatoid Arthritis

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Hybrid Molecules Consisting of Lysine Dendrons with Several Hydrophobic Tails: A SCF Study of Self-Assembling

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Synthesis and Anticancer Activity of Hybrid Molecules Based on Lithocholic and (5Z,9Z)-Tetradeca-5,9-dienedioic Acids Linked via Mono(di,tri,tetra)ethylene Glycol and α,ω-Diaminoalkane Units

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Synthesis of Hybrid Molecules with Imidazole-1,3,4-thiadiazole Core and Evaluation of Biological Activity on Trypanosoma cruzi and Leishmania donovani

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Hybrid Molecules Composed of 2,4-Diamino-1,3,5-triazines and 2-Imino-Coumarins and Coumarins. Synthesis and Cytotoxic Properties

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Conjugation as a Tool in Therapeutics: Role of Amino Acids/Peptides-Bioactive (Including Heterocycles) Hybrid Molecules in Treating Infectious Diseases

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Xanthine–Dopamine Hybrid Molecules as Multitarget Drugs with Potential for the Treatment of Neurodegenerative Diseases

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Molecular mechanisms of bifunctional vitamin D receptor agonist-histone deacetylase inhibitor hybrid molecules in triple-negative breast cancer

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Hybrid Molecules of Azithromycin with Chloramphenicol and Metronidazole: Synthesis and Study of Antibacterial Properties

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Atom-efficient synthesis of hybrid molecules combining fragments of triazolopyrimidines and 3-ethoxycarbonyl-1-ethyl-6-fluoroquinolin-4(1H)-one through 1,2,3-triazole linker

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Design and synthesis of some novel hybrid molecules based on 4-thiazolidinone bearing pyridine-pyrazole scaffolds: molecular docking and molecular dynamics simulations of its major constituent onto DN...

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Design, synthesis and biological evaluation of novel 1,2,3-triazolyl [beta]-hydroxy alkyl/carbazole hybrid molecules

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Synthesis, molecular docking and anti-diabetic studies of novel benzimidazole-pyrazoline hybrid molecules

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