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ArticlesPeer ReviewedFull Text
Immunogenicity of somatic mutations in human gastrointestinal cancers
Author / Creator:Tran, Eric ; Ahmadzadeh, Mojgan ; Lu, Yong-Chen ; Gros, Alena ; Turcotte, Simon ; Robbins, Paul F. ; Gartner, Jared J. ; Zheng, Zhili ; Li, Yong F. ; Ray, Satyajit ; Wunderlich, John R. ; Somerville, Robert P. ; Rosenberg, Steven A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-12, Vol.350 (6266), p.1387-1390
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Genetic Associations with Gestational Duration and Spontaneous Preterm Birth
Author / Creator:Zhang, Ge ; Feenstra, Bjarke ; Bacelis, Jonas ; Liu, Xueping ; Muglia, Lisa M ; Juodakis, Julius ; Miller, Daniel E ; Litterman, Nadia ; Jiang, Pan-Pan ; Russell, Laura ; Hinds, David A ; Hu, Youna ; Weirauch, Matthew T ; Chen, Xiaoting ; Chavan, Arun R ; Wagner, Günter P ; Pavličev, Mihaela ; Nnamani, Mauris C ; Maziarz, Jamie ; Karjalainen, Minna K ; Rämet, Mika ; Sengpiel, Verena ; Geller, Frank ; Boyd, Heather A ; Palotie, Aarno ; Momany, Allison ; Bedell, Bruce ; Ryckman, Kelli K ; Huusko, Johanna M ; Forney, Carmy R ; Kottyan, Leah C ; Hallman, Mikko ; Teramo, Kari ; Nohr, Ellen A ; Davey Smith, George ; Melbye, Mads ; Jacobsson, Bo ; Muglia, Louis J
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-09, Vol.377 (12), p.1156-1167
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Deconvoluting the context-dependent role for autophagy in cancer
Author / Creator:White, Eileen
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2012-06, Vol.12 (6), p.401-410
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The RASopathy Family: Consequences of Germline Activation of the RAS/MAPK Pathway
Author / Creator:Tajan, Mylène ; Paccoud, Romain ; Branka, Sophie ; Edouard, Thomas ; Yart, Armelle
Publisher:Washington, DC: Endocrine Society
Journal title:Endocrine reviews, 2018-10, Vol.39 (5), p.676-700
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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers
Author / Creator:Landa, Iñigo ; Ibrahimpasic, Tihana ; Boucai, Laura ; Sinha, Rileen ; Knauf, Jeffrey A ; Shah, Ronak H ; Dogan, Snjezana ; Ricarte-Filho, Julio C ; Krishnamoorthy, Gnana P ; Xu, Bin ; Schultz, Nikolaus ; Berger, Michael F ; Sander, Chris ; Taylor, Barry S ; Ghossein, Ronald ; Ganly, Ian ; Fagin, James A
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-03, Vol.126 (3), p.1052-1066
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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...
Author / Creator:Cremolini, Chiara, MD ; Loupakis, Fotios, PhD ; Antoniotti, Carlotta, MD ; Lupi, Cristiana, BSc ; Sensi, Elisa, PhD ; Lonardi, Sara, MD ; Mezi, Silvia, MD ; Tomasello, Gianluca, MD ; Ronzoni, Monica, MD ; Zaniboni, Alberto, MD ; Tonini, Giuseppe, Prof ; Carlomagno, Chiara, PhD ; Allegrini, Giacomo, MD ; Chiara, Silvana, MD ; D'Amico, Mauro, MD ; Granetto, Cristina, MD ; Cazzaniga, Marina, MD ; Boni, Luca, MD ; Fontanini, Gabriella, Prof ; Falcone, Alfredo, Prof
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1306-1315
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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients
Author / Creator:Siravegna, Giulia ; Mussolin, Benedetta ; Buscarino, Michela ; Corti, Giorgio ; Cassingena, Andrea ; Crisafulli, Giovanni ; Ponzetti, Agostino ; Cremolini, Chiara ; Amatu, Alessio ; Lauricella, Calogero ; Lamba, Simona ; Hobor, Sebastijan ; Avallone, Antonio ; Valtorta, Emanuele ; Rospo, Giuseppe ; Medico, Enzo ; Motta, Valentina ; Antoniotti, Carlotta ; Tatangelo, Fabiana ; Bellosillo, Beatriz ; Veronese, Silvio ; Budillon, Alfredo ; Montagut, Clara ; Racca, Patrizia ; Marsoni, Silvia ; Falcone, Alfredo ; Corcoran, Ryan B ; Di Nicolantonio, Federica ; Loupakis, Fotios ; Siena, Salvatore ; Sartore-Bianchi, Andrea ; Bardelli, Alberto
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-07, Vol.21 (7), p.795-801
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ArticlesPeer ReviewedFull Text
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids
Author / Creator:Huang, Ling ; Holtzinger, Audrey ; Jagan, Ishaan ; BeGora, Michael ; Lohse, Ines ; Ngai, Nicholas ; Nostro, Cristina ; Wang, Rennian ; Muthuswamy, Lakshmi B ; Crawford, Howard C ; Arrowsmith, Cheryl ; Kalloger, Steve E ; Renouf, Daniel J ; Connor, Ashton A ; Cleary, Sean ; Schaeffer, David F ; Roehrl, Michael ; Tsao, Ming-Sound ; Gallinger, Steven ; Keller, Gordon ; Muthuswamy, Senthil K
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-11, Vol.21 (11), p.1364-1371
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ArticlesPeer ReviewedFull Text
Multitarget Stool DNA Testing for Colorectal-Cancer Screening
Author / Creator:Imperiale, Thomas F ; Ransohoff, David F ; Itzkowitz, Steven H ; Levin, Theodore R ; Lavin, Philip ; Lidgard, Graham P ; Ahlquist, David A ; Berger, Barry M
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2014-04, Vol.370 (14), p.1287-1297
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Select record 30
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Oncogenic KRAS signalling in pancreatic cancer
Author / Creator:Eser, S ; Schnieke, A ; Schneider, G ; Saur, D
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2014-08, Vol.111 (5), p.817-822
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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Author / Creator:Son, Jaekyoung ; Lyssiotis, Costas A. ; Ying, Haoqiang ; Wang, Xiaoxu ; Hua, Sujun ; Ligorio, Matteo ; Perera, Rushika M. ; Ferrone, Cristina R. ; Mullarky, Edouard ; Shyh-Chang, Ng ; Kang, Ya’an ; Fleming, Jason B. ; Bardeesy, Nabeel ; Asara, John M. ; Haigis, Marcia C. ; DePinho, Ronald A. ; Cantley, Lewis C. ; Kimmelman, Alec C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-04, Vol.496 (7443), p.101-105
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Select record 32
ArticlesPeer ReviewedFull Text
In situ sequencing for RNA analysis in preserved tissue and cells
Author / Creator:Ke, Rongqin ; Mignardi, Marco ; Pacureanu, Alexandra ; Svedlund, Jessica ; Botling, Johan ; Wählby, Carolina ; Nilsson, Mats
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2013-09, Vol.10 (9), p.857-860
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Select record 33
ArticlesPeer ReviewedFull Text
Genomic alterations in lung adenocarcinoma
Author / Creator:Devarakonda, Siddhartha, MD ; Morgensztern, Daniel, MD ; Govindan, Ramaswamy, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-07, Vol.16 (7), p.e342-e351
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ArticlesPeer ReviewedFull Text
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations
Author / Creator:Eleveld, Thomas F ; Oldridge, Derek A ; Bernard, Virginie ; Koster, Jan ; Daage, Leo Colmet ; Diskin, Sharon J ; Schild, Linda ; Bentahar, Nadia Bessoltane ; Bellini, Angela ; Chicard, Mathieu ; Lapouble, Eve ; Combaret, Valérie ; Legoix-Né, Patricia ; Michon, Jean ; Pugh, Trevor J ; Hart, Lori S ; Rader, JulieAnn ; Attiyeh, Edward F ; Wei, Jun S ; Zhang, Shile ; Naranjo, Arlene ; Gastier-Foster, Julie M ; Hogarty, Michael D ; Asgharzadeh, Shahab ; Smith, Malcolm A ; Guidry Auvil, Jaime M ; Watkins, Thomas B K ; Zwijnenburg, Danny A ; Ebus, Marli E ; van Sluis, Peter ; Hakkert, Anne ; van Wezel, Esther ; van der Schoot, C Ellen ; Westerhout, Ellen M ; Schulte, Johannes H ; Tytgat, Godelieve A ; Dolman, M Emmy M ; Janoueix-Lerosey, Isabelle ; Gerhard, Daniela S ; Caron, Huib N ; Delattre, Olivier ; Khan, Javed ; Versteeg, Rogier ; Schleiermacher, Gudrun ; Molenaar, Jan J ; Maris, John M
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2015-08, Vol.47 (8), p.864-871
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Protein prenylation: unique fats make their mark on biology
Author / Creator:Wang, Mei ; Casey, Patrick J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2016-02, Vol.17 (2), p.110-122
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Select record 36
ArticlesPeer ReviewedFull Text
Testicular germ cell tumours
Author / Creator:Rajpert-De Meyts, Ewa, DMSc ; McGlynn, Katherine A, PhD ; Okamoto, Keisei, Dr ; Jewett, Michael A S, Prof ; Bokemeyer, Carsten, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2016-04, Vol.387 (10029), p.1762-1774
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Select record 37
ArticlesPeer ReviewedFull Text
Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA
Author / Creator:Thierry, Alain R ; Mouliere, Florent ; El Messaoudi, Safia ; Mollevi, Caroline ; Lopez-Crapez, Evelyne ; Rolet, Fanny ; Gillet, Brigitte ; Gongora, Celine ; Dechelotte, Pierre ; Robert, Bruno ; Del Rio, Maguy ; Lamy, Pierre-Jean ; Bibeau, Frederic ; Nouaille, Michelle ; Loriot, Virginie ; Jarrousse, Anne-Sophie ; Molina, Franck ; Mathonnet, Muriel ; Pezet, Denis ; Ychou, Marc
Publisher:New York: Nature Publishing Group US
Journal title:Nature Medicine, 2014-04, Vol.20 (4), p.430-435
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Select record 38
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Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
Author / Creator:Al-Olabi, Lara ; Polubothu, Satyamaanasa ; Dowsett, Katherine ; Andrews, Katrina A ; Stadnik, Paulina ; Joseph, Agnel P ; Knox, Rachel ; Pittman, Alan ; Clark, Graeme ; Baird, William ; Bulstrode, Neil ; Glover, Mary ; Gordon, Kristiana ; Hargrave, Darren ; Huson, Susan M ; Jacques, Thomas S ; James, Gregory ; Kondolf, Hannah ; Kangesu, Loshan ; Keppler-Noreuil, Kim M ; Khan, Amjad ; Lindhurst, Marjorie J ; Lipson, Mark ; Mansour, Sahar ; O'Hara, Justine ; Mahon, Caroline ; Mosica, Anda ; Moss, Celia ; Murthy, Aditi ; Ong, Juling ; Parker, Victoria E ; Rivière, Jean-Baptiste ; Sapp, Julie C ; Sebire, Neil J ; Shah, Rahul ; Sivakumar, Branavan ; Thomas, Anna ; Virasami, Alex ; Waelchli, Regula ; Zeng, Zhiqiang ; Biesecker, Leslie G ; Barnacle, Alex ; Topf, Maya ; Semple, Robert K ; Patton, E Elizabeth ; Kinsler, Veronica A
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-04, Vol.128 (4), p.1496-1508
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Select record 39
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ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications
Author / Creator:Yi, Ming ; Nissley, Dwight V. ; McCormick, Frank ; Stephens, Robert M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-06, Vol.10 (1), p.10258, Article 10258
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Select record 40
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Selumetinib plus docetaxel for KRAS -mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study
Author / Creator:Jänne, Pasi A, Dr ; Shaw, Alice T, MD ; Pereira, José Rodrigues, MD ; Jeannin, Gaëlle, MD ; Vansteenkiste, Johan, Prof ; Barrios, Carlos, MD ; Franke, Fabio Andre, MD ; Grinsted, Lynda, MSc ; Zazulina, Victoria, MD ; Smith, Paul, PhD ; Smith, Ian, MD ; Crinò, Lucio, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013, Vol.14 (1), p.38-47
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Immunogenicity of somatic mutations in human gastrointestinal cancers

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Genetic Associations with Gestational Duration and Spontaneous Preterm Birth

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Deconvoluting the context-dependent role for autophagy in cancer

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The RASopathy Family: Consequences of Germline Activation of the RAS/MAPK Pathway

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Genomic and transcriptomic hallmarks of poorly differentiated and anaplastic thyroid cancers

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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...

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Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

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Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids

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Multitarget Stool DNA Testing for Colorectal-Cancer Screening

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Oncogenic KRAS signalling in pancreatic cancer

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Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway

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In situ sequencing for RNA analysis in preserved tissue and cells

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Genomic alterations in lung adenocarcinoma

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Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations

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Protein prenylation: unique fats make their mark on biology

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Testicular germ cell tumours

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Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

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Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy

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ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications

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Selumetinib plus docetaxel for KRAS -mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study

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