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119 results for Piperidones+-+pharmacology

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Select record 41
ArticlesPeer ReviewedFull Text
Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines
Author / Creator:Swain, Risa Mia ; Contreras, Lisett ; Varela-Ramirez, Armando ; Hossain, Mohammad ; Das, Umashankar ; Valenzuela, Carlos A. ; Penichet, Manuel L. ; Dimmock, Jonathan R. ; Aguilera, Renato J
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2022-10, Vol.40 (5), p.905-921
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Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis
Author / Creator:Nan, Ling ; Jacko, Anastasia M. ; Tan, Jiangning ; Wang, Dan ; Zhao, Jing ; Kass, Daniel J. ; Ma, Haichun ; Zhao, Yutong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-09, Vol.6 (1), p.33116-33116, Article 33116
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The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5
Author / Creator:Oh, You-Take ; Deng, Liang ; Deng, Jiusheng ; Sun, Shi-Yong
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-08, Vol.7 (1), p.8027-11, Article 8027
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Biological and physical approaches on the role of piplartine (piperlongumine) in cancer
Author / Creator:Henrique, Tiago ; Zanon, Caroline de F. ; Girol, Ana P. ; Stefanini, Ana Carolina Buzzo ; Contessoto, Nayara S. de A. ; da Silveira, Nelson J. F. ; Bezerra, Daniel P. ; Silveira, Edilberto R. ; Barbosa-Filho, José M. ; Cornélio, Marinonio L. ; Oliani, Sonia M. ; Tajara, Eloiza H.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-12, Vol.10 (1), p.22283-14, Article 22283
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Select record 45
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Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma
Author / Creator:Da Nóbrega, Flávio Rogério ; Ozdemir, Ozlem ; Nascimento Sousa, Sheila Cristina S. ; Barboza, Joice Nascimento ; Turkez, Hasan ; De Sousa, Damião Pergentino
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1382
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Select record 46
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The PDE4 Inhibitor HT-0712 Improves Hippocampus-Dependent Memory in Aged Mice
Author / Creator:Peters, Marco ; Bletsch, Matthew ; Stanley, Jennifer ; Wheeler, Damian ; Scott, Roderick ; Tully, Tim
Publisher:Basingstoke: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2014-12, Vol.39 (13), p.2938-2948
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Select record 47
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Antileishmanial activity evaluation of a natural amide and its synthetic analogs against Leishmania (V.) braziliensis: an integrated approach in vitro and in silico
Author / Creator:da Silva, Minelly A. ; Fokoue, Harold H. ; Fialho, Saara N. ; dos Santos, Ana Paula de A. ; Rossi, Norton R. D. L. P. ; Gouveia, Aurileya de J. ; Ferreira, Amália S. ; Passarini, Guilherme M. ; Garay, Ana F. G. ; Alfonso, Jorge J. ; Soares, Andreimar M. ; Zanchi, Fernando B. ; Kato, Massuo J. ; Teles, Carolina B. G. ; Kuehn, Christian C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Parasitology research (1987), 2021-06, Vol.120 (6), p.2199-2218
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Select record 48
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CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells
Author / Creator:Yang, Jia-Sin ; Lin, Renn-Chia ; Hsieh, Yi-Hsien ; Wu, Heng-Hsiung ; Li, Geng-Chung ; Lin, Ya-Chiu ; Yang, Shun-Fa ; Lu, Ko-Hsiu
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-09, Vol.24 (18), p.3280
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Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer
Author / Creator:Chen, Shuli ; Nimick, Mhairi ; Cridge, Andrew ; Hawkins, Bill ; Rosengren, Rhonda
Publisher:Athens: Spandidos Publications
Journal title:International journal of oncology, 2018-02, Vol.52 (2), p.579-588
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The novel deubiquitinase inhibitor b-AP15 induces direct and NK cell-mediated antitumor effects in human mantle cell lymphoma
Author / Creator:Kropp, Korbinian N. ; Maurer, Stefanie ; Rothfelder, Kathrin ; Schmied, Bastian J. ; Clar, Kim L. ; Schmidt, Moritz ; Strunz, Benedikt ; Kopp, Hans-Georg ; Steinle, Alexander ; Grünebach, Frank ; Rittig, Susanne M. ; Salih, Helmut R. ; Dörfel, Daniela
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2018-06, Vol.67 (6), p.935-947
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Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment
Author / Creator:Zubarev, Roman A. ; D'Arcy, Padraig ; Saei, Amir Ata ; Espinosa, Belén ; Zhang, Xiaonan ; Linder, Stig
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:Oxidative medicine and cellular longevity, 2019-01, Vol.2019 (2019), p.1-11
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DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling
Author / Creator:Sasi, Nanda Kumar ; Coquel, Flavie ; Lin, Yea-Lih ; Mackeigan, Jeffrey ; Pasero, Philippe ; Weinreich, Michael
Publisher:Springer Verlag (Germany)
Journal title:Journal of mammary gland biology and neoplasia, 2018-10, Vol.20 (10), p.985-995
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Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells
Author / Creator:Campelo, Yuri ; Ombredane, Alicia ; Vasconcelos, Andreanne ; Albuquerque, Lucas ; Moreira, Daniel ; Plácido, Alexandra ; Rocha, Jefferson ; Hilarion Fokoue, Harold ; Yamaguchi, Lydia ; Mafud, Ana ; Mascarenhas, Yvonne ; Delerue-Matos, Cristina ; Borges, Tatiana ; Joanitti, Graziella ; Arcanjo, Daniel ; Kato, Massuo ; Kuckelhaus, Selma ; Silva, Marcos ; De Moraes, Josué ; Leite, José
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2018-06, Vol.19 (6), p.1802
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Select record 54
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A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity
Author / Creator:Montagnoli, Alessia ; Valsasina, Barbara ; Croci, Valter ; Menichincheri, Maria ; Rainoldi, Sonia ; Marchesi, Vanessa ; Tibolla, Marcello ; Tenca, Pierluigi ; Brotherton, Deborah ; Albanese, Clara ; Patton, Veronica ; Alzani, Rachele ; Ciavolella, Antonella ; Sola, Francesco ; Molinari, Antonio ; Volpi, Daniele ; Avanzi, Nilla ; Fiorentini, Francesco ; Cattoni, Marina ; Healy, Sandra ; Ballinari, Dario ; Pesenti, Enrico ; Isacchi, Antonella ; Moll, Jurgen ; Bensimon, Aaron ; Vanotti, Ermes ; Santocanale, Corrado
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2008-06, Vol.4 (6), p.357-365
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The Dose-Dependent Organ-Specific Effects of a Dipeptidyl Peptidase-4 Inhibitor on Cardiovascular Complications in a Model of Type 2 Diabetes
Author / Creator:Moon, Ju-Young ; Woo, Jong Shin ; Seo, Jung-Woo ; Lee, Arah ; Kim, Dong Jin ; Kim, Yang-Gyun ; Kim, Se-Yeun ; Lee, Kyung Hye ; Lim, Sung-Jig ; Cheng, Xian Wu ; Lee, Sang-Ho ; Kim, Weon
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-03, Vol.11 (3), p.e0150745-e0150745
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Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases
Author / Creator:Chung, Yu-Han ; Lin, Chia-Wei ; Huang, Hsin-Yu ; Chen, Shu-Ling ; Huang, Hei-Jen ; Sun, Ying-Chieh ; Lee, Guan-Chiun ; Lee-Chen, Guey-Jen ; Chang, Ya-Ching ; Hsieh-Li, Hsiu Mei
Publisher:New York: Springer US
Journal title:Journal of molecular neuroscience, 2020-07, Vol.70 (7), p.1140-1152
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Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation
Author / Creator:Liu, Hsiu-Yu ; Tuckett, Andrea Z. ; Fennell, Myles ; Garippa, Ralph ; Zakrzewski, Johannes L.
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2018-08, Vol.36 (4), p.590-600
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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells
Author / Creator:Al-Howail, Huda A. ; Hakami, Hana A. ; Al-Otaibi, Basem ; Al-Mazrou, Amer ; Daghestani, Maha H. ; Al-Jammaz, Ibrahim ; Al-Khalaf, Huda H. ; Aboussekhra, Abdelilah
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2016-07, Vol.16 (1), p.540-540, Article 540
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11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model
Author / Creator:Puigoriol-Illamola, Dolors ; Griñán-Ferré, Christian ; Vasilopoulou, Foteini ; Leiva, Rosana ; Vázquez, Santiago ; Pallàs, Mercè
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2018-12, Vol.55 (12), p.8904-8915
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Select record 60
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A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies
Author / Creator:Bisht, Savita ; Schlesinger, Martin ; Rupp, Alexander ; Schubert, Rolf ; Nolting, Jens ; Wenzel, Jörg ; Holdenrieder, Stefan ; Brossart, Peter ; Bendas, Gerd ; Feldmann, Georg
Publisher:England: BioMed Central Ltd
Journal title:Journal of nanobiotechnology, 2016-07, Vol.14 (1), p.57-57, Article 57
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Showing 41 to 60 of 119 results

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Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines

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Ubiquitin carboxyl-terminal hydrolase-L5 promotes TGFβ-1 signaling by de-ubiquitinating and stabilizing Smad2/Smad3 in pulmonary fibrosis

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The proteasome deubiquitinase inhibitor b-AP15 enhances DR5 activation-induced apoptosis through stabilizing DR5

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Biological and physical approaches on the role of piplartine (piperlongumine) in cancer

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Piplartine Analogues and Cytotoxic Evaluation against Glioblastoma

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The PDE4 Inhibitor HT-0712 Improves Hippocampus-Dependent Memory in Aged Mice

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Antileishmanial activity evaluation of a natural amide and its synthetic analogs against Leishmania (V.) braziliensis: an integrated approach in vitro and in silico

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CLEFMA Activates the Extrinsic and Intrinsic Apoptotic Processes through JNK1/2 and p38 Pathways in Human Osteosarcoma Cells

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Anticancer potential of novel curcumin analogs towards castrate-resistant prostate cancer

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The novel deubiquitinase inhibitor b-AP15 induces direct and NK cell-mediated antitumor effects in human mantle cell lymphoma

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Oxidative Stress Induced by the Deubiquitinase Inhibitor b-AP15 Is Associated with Mitochondrial Impairment

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DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling

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Structure–Activity Relationship of Piplartine and Synthetic Analogues against Schistosoma mansoni and Cytotoxicity to Mammalian Cells

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A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity

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The Dose-Dependent Organ-Specific Effects of a Dipeptidyl Peptidase-4 Inhibitor on Cardiovascular Complications in a Model of Type 2 Diabetes

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Targeting Inflammation, PHA-767491 Shows a Broad Spectrum in Protein Aggregation Diseases

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Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation

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PAC down-regulates estrogen receptor alpha and suppresses epithelial-to-mesenchymal transition in breast cancer cells

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11β-HSD1 Inhibition by RL-118 Promotes Autophagy and Correlates with Reduced Oxidative Stress and Inflammation, Enhancing Cognitive Performance in SAMP8 Mouse Model

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A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies

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