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Long Term Amlodipine Administration Caused Infertility in Wistar Rat: A Paradoxically Safe Contraceptive
Author / Creator:Ogunnaike, P O ; Olatunji, S Y ; Owolabi, J O ; Olawuyi, D D ; Adelodun, S T
Publisher:Lagos: Michael Joanna Publications
Journal title:International journal of medicine and biomedical research, 2019-01, Vol.8 (1), p.1-11
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ArticlesPeer ReviewedFull Text
Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review
Author / Creator:Chow, Clara K, Prof ; Thakkar, Jay, MBBS ; Bennett, Alex, MPhil ; Hillis, Graham, Prof ; Burke, Michael, PhD ; Usherwood, Tim, Prof ; Vo, Kha, BSc ; Rogers, Kris, PhD ; Atkins, Emily, PhD ; Webster, Ruth, PhD ; Chou, Michael, MBBS ; Dehbi, Hakim-Moulay, MRes ; Salam, Abdul, PhD ; Patel, Anushka, Prof ; Neal, Bruce, Prof ; Peiris, David, PhD ; Krum, Henry, Prof ; Chalmers, John, Prof ; Nelson, Mark, Prof ; Reid, Christopher M, Prof ; Woodward, Mark, Prof ; Hilmer, Sarah, Prof ; Thom, Simon, Prof ; Rodgers, Anthony, Prof
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2017-03, Vol.389 (10073), p.1035-1042
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Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Card...
Author / Creator:Dahlöf, Björn ; Sever, Peter S ; Poulter, Neil R ; Wedel, Hans ; Beevers, D Gareth ; Caulfield, Mark ; Collins, Rory ; Kjeldsen, Sverre E ; Kristinsson, Arni ; McInnes, Gordon T ; Mehlsen, Jesper ; Nieminen, Markku ; O'Brien, Eoin ; Östergren, Jan
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2005-09, Vol.366 (9489), p.895-906
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Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3,...
Author / Creator:Chow, Clara K ; Atkins, Emily R ; Hillis, Graham S ; Nelson, Mark R ; Reid, Christopher M ; Schlaich, Markus P ; Hay, Peter ; Rogers, Kris ; Billot, Laurent ; Burke, Michael ; Chalmers, John ; Neal, Bruce ; Patel, Anushka ; Usherwood, Tim ; Webster, Ruth ; Rodgers, Anthony ; Hung, Andrew ; Edison, Armand ; Abraham, Angalie E ; Xu, Daniel ; Bloch, Mark T ; Figtree, Gemma ; Nolde, Janis M ; Black, Andrew ; Jansen, Shirley ; Biswas, Sinjini ; Ajani, Andrew E ; Carnagarin, Revathy ; Wynne, Dylan ; Altman, Mikhail ; Thakkar, Jay ; Thiagalingam, Aravinda ; Klimis, Harry
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2021-09, Vol.398 (10305), p.1043-1052
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ArticlesPeer ReviewedFull Text
Polypill for Cardiovascular Disease Prevention in an Underserved Population
Author / Creator:Muñoz, Daniel ; Uzoije, Prince ; Reynolds, Cassandra ; Miller, Roslynn ; Walkley, David ; Pappalardo, Susan ; Tousey, Phyllis ; Munro, Heather ; Gonzales, Holly ; Song, Wenliang ; White, Charles ; Blot, William J ; Wang, Thomas J
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-09, Vol.381 (12), p.1114-1123
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ArticlesPeer ReviewedFull Text
Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans
Author / Creator:Ojji, Dike B ; Mayosi, Bongani ; Francis, Veronica ; Badri, Motasim ; Cornelius, Victoria ; Smythe, Wynand ; Kramer, Nicky ; Barasa, Felix ; Damasceno, Albertino ; Dzudie, Anastase ; Jones, Erika ; Mondo, Charles ; Ogah, Okechukwu ; Ogola, Elijah ; Sani, Mahmoud U ; Shedul, Gabriel L ; Shedul, Grace ; Rayner, Brian ; Okpechi, Ikechi G ; Sliwa, Karen ; Poulter, Neil
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-06, Vol.380 (25), p.2429-2439
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Efficacy and safety of a novel low-dose triple single-pill combination of telmisartan, amlodipine and indapamide, compared with dual combinations for treatment of hypertension: a randomised, double-bl...
Author / Creator:Rodgers, Anthony ; Salam, Abdul ; Schutte, Aletta E ; Cushman, William C ; de Silva, H Asita ; Di Tanna, Gian Luca ; Grobbee, Diederick E ; Narkiewicz, Krzysztof ; Ojji, Dike B ; Poulter, Neil R ; Schlaich, Markus P ; Oparil, Suzanne ; Spiering, Wilko ; Williams, Bryan ; Wright, Jackson T ; Lakshman, P ; Uluwattage, W ; Hay, P ; Pereira, T ; Amarasena, N ; Ranasinghe, G ; Gianacas, Chris ; Shanthakumar, Mathangi ; Liu, Xiaoqiu ; Wang, Nelson ; Gnanenthiran, Sonali R ; Whelton, Paul K
Publisher:England: Elsevier Ltd
Journal title:The Lancet (British edition), 2024-10, Vol.404 (10462), p.1536-1546
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Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised cont...
Author / Creator:Bakris, George L, Dr, Prof ; Sarafidis, Pantelis A, MD ; Weir, Matthew R, Prof ; Dahlöf, Björn, Prof ; Pitt, Bertram, Prof ; Jamerson, Kenneth, MD ; Velazquez, Eric J, MD ; Staikos-Byrne, Linda, PhD ; Kelly, Roxzana Y, MS ; Shi, Victor, MD ; Chiang, Yann-Tong, PhD ; Weber, Michael A, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2010-04, Vol.375 (9721), p.1173-1181
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Initial treatment with a single capsule containing half-dose quadruple therapy vs standard-dose dual therapy in hypertensive patients (QUADUAL): a randomized, blinded, crossover trial
Author / Creator:Zhao, Xiexiong ; Liu, Tao ; Yang, Qiong ; Yang, Guoping ; Li, Xingli ; Tang, Xiaohong ; Li, Jingle ; Liang, Zhongshu ; Li, Anying ; Zeng, Lixiong ; Wen, Juan ; Wang, Xiaoyan ; Peng, Liping ; Wang, Wenjuan ; Cai, Jingjing ; Chen, Ye ; Huang, Miao ; Li, Ruixuan ; Fu, Ru ; Zhao, Lin ; Li, Xiaogang ; Jiang, Weihong
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2025-01, Vol.23 (1), p.56-13, Article 56
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The Efficacy and Tolerability of Irbesartan/Amlodipine Combination Therapy in Patients With Essential Hypertension Whose Blood Pressure Were not Controlled by Irbesartan Monotherapy
Author / Creator:Lee, Hae-Young, MD ; Min, Kyung Wan, MD ; Han, Kyung Ah, MD ; Kim, Jeong Su, MD ; Ahn, Jeong Cheon, MD ; Kim, Moo Hyun, MD ; Lee, Jin Bae, MD ; Shin, Sung-Hee, MD ; Kim, Chong-Jin, MD ; Kim, Kye Hun, MD ; Cho, Deok-Kyu, MD ; Choi, Junghyun, MD ; Rhee, Moo-Yong, MD ; Her, Sung-Ho, MD ; Kim, Weon, MD ; Na, Jin Oh, MD ; Cho, Goo-Yeong, MD ; Kim, Seok Yeon, MD ; Park, Gyung-Min, MD ; Lee, Bong-Ki, MD ; Jo, Sang-Ho, MD ; Lee, Byung Wan, MD ; Sohn, Il-Suk, MD ; Kim, Doo-Il, MD ; Ihm, Sang-Hyun, MD ; Lee, Sun Hwa, MD ; Chung, Joong-Wha, MD ; Cho, Eun Joo, MD ; Son, Jang Won, MD ; Oh, Seung-Jin, MD ; Hwang, Jin-Yong, MD ; Jeong, Jin-Ok, MD ; Han, Kyoo-Rok, MD ; Yoon, Hyuck-Jun, MD ; Seo, Suk Min, MD ; Chung, Wook-Jin, MD ; Bae, Jang-Whan, MD ; Choi, Jin-Ho, MD ; Hyun, Bok Jin ; Cha, Ji Eun ; Yoo, Seung Ji ; Shin, Jinho, MD
Publisher:United States: Elsevier Inc
Journal title:Clinical therapeutics, 2024-06, Vol.46 (6), p.481-489
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ArticlesPeer ReviewedFull Text
Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol
Author / Creator:Chow, Clara K. ; Atkins, Emily R. ; Billot, Laurent ; Chalmers, John ; Hillis, Graham S. ; Hay, Peter ; Neal, Bruce ; Nelson, Mark ; Patel, Anushka ; Reid, Christopher M. ; Schlaich, Markus ; Usherwood, Tim ; Webster, Ruth ; Rodgers, Anthony
Publisher:United States: Elsevier Inc
Journal title:The American heart journal, 2021-01, Vol.231, p.56-67
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ArticlesPeer ReviewedFull Text
Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled by Amlodipine: A Phase III, Multicenter, Double‐Blind, Parallel‐Group, Randomized Controlled...
Author / Creator:Chi, Hongjie ; Zhang, Xin ; Ma, Shumei ; Pan, Gang ; Lian, Xiaojuan ; Chen, Yan ; Pei, Haotian ; Liu, Zichen ; Lin, Xiangmin
Publisher:United States: John Wiley & Sons, Inc
Journal title:The journal of clinical hypertension (Greenwich, Conn.), 2025-01, Vol.27 (1), p.e14955-n/a
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ArticlesPeer ReviewedFull Text
Phase III randomized clinical trial of efficacy and safety of amlodipine and candesartan cilexetil combination for hypertension treatment
Author / Creator:Soh, Moon-Seung ; Won, Kyung-heon ; Kim, Jae-Joong ; Lee, Sung Yun ; Hyon, Min Su ; Youn, Ho-Joong ; Rha, Seung-Woon ; Kim, Doo-Il ; Ahn, Youngkeun ; Kim, Byung Jin ; Choi, Dong-Ju ; Park, Jong-Seon ; Kim, Dae-Kyung ; Park, Woo-Jung ; Lim, Hong-Seok ; Tahk, Seung-Jea
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.22940-12, Article 22940
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ArticlesPeer ReviewedFull Text
Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial
Author / Creator:Weber, Michael A, Prof ; Jamerson, Kenneth, Prof ; Bakris, George L, Prof ; Weir, Matthew R, Prof ; Zappe, Dion, PhD ; Zhang, Ying, PhD ; Dahlof, Bjorn, MD ; Velazquez, Eric J, MD ; Pitt, Bertram, Prof
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2013-02, Vol.381 (9866), p.537-545
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Randomized Polypill crossover trial in people aged 50 and over
Author / Creator:Wald, David S ; Morris, Joan K ; Wald, Nicholas J
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-07, Vol.7 (7), p.e41297-e41297
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Efficacy of Olmesartan/Amlodipine Single‐Pill Combination on 24‐h Mean Systolic Blood Pressure Measured by Ambulatory Monitoring in Non‐Responders to Valsartan or Candesartan Monotherapy
Author / Creator:Chung, Woo‐Baek ; Ihm, Sang‐Hyun ; Choi, Yun‐Seok ; Youn, Ho‐Joong
Publisher:United States: John Wiley & Sons, Inc
Journal title:The journal of clinical hypertension (Greenwich, Conn.), 2025-01, Vol.27 (1), p.e14929-n/a
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Pharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects
Author / Creator:Tian, Mengli ; Huang, Jinlong ; Chen, Yingrong ; Jin, Qiuyue ; Jiang, Hong ; Shi, Cunyuan ; Mei, Jue ; Xu, Min ; Yu, Xiang ; Yang, Shuixin
Publisher:New Zealand: Dove
Journal title:Drug design, development and therapy, 2025-01, Vol.19, p.11-22
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Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)
Author / Creator:Yamamoto, Koichi ; Yarimizu, Daisuke ; Shimanishi, Ayano ; Eguchi, Shunsuke ; Iekushi, Kazuma ; Takami, Yoichi ; Nozato, Yoichi ; Kario, Kazuomi ; Rakugi, Hiromi
Publisher:United States: John Wiley & Sons, Inc
Journal title:The journal of clinical hypertension (Greenwich, Conn.), 2025-01, Vol.27 (1), p.e14938-n/a
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The antihypertensive efficacy of a quadruple single-pill combination in patients with resistant hypertension: study protocol for a randomized, open-label, crossover trial
Author / Creator:Yao, Yuanyuan ; Zhang, Xin ; Ye, Runyu ; Jia, Shanshan ; Yang, Xiangyu ; Chen, Xiaoping
Publisher:England: BioMed Central Ltd
Journal title:Current controlled trials in cardiovascular medicine, 2025-01, Vol.26 (1), p.22-11, Article 22
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Randomised controlled decentralised feasibility trial of a fixed low-dose combination antihypertensive drug strategy to attenuate cognitive decline in high-risk adults
Author / Creator:Carcel, Cheryl ; Clancy, Lauren ; Harris, Katie ; Peters, Ruth ; Byrne, Aisling ; Bassett, Kimberley ; Freed, Ruth ; Hoyos, Camilla M ; Rodgers, Anthony ; Lindley, Richard ; Chalmers, John ; Xu, Ying ; Woodward, Mark ; Ouyang, Menglu ; Naismith, Sharon L ; Anderson, Craig
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ open, 2024-08, Vol.14 (8), p.e080862
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Long Term Amlodipine Administration Caused Infertility in Wistar Rat: A Paradoxically Safe Contraceptive

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Quarter-dose quadruple combination therapy for initial treatment of hypertension: placebo-controlled, crossover, randomised trial and systematic review

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Prevention of cardiovascular events with an antihypertensive regimen of amlodipine adding perindopril as required versus atenolol adding bendroflumethiazide as required, in the Anglo-Scandinavian Card...

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Initial treatment with a single pill containing quadruple combination of quarter doses of blood pressure medicines versus standard dose monotherapy in patients with hypertension (QUARTET): a phase 3,...

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Polypill for Cardiovascular Disease Prevention in an Underserved Population

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Comparison of Dual Therapies for Lowering Blood Pressure in Black Africans

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Efficacy and safety of a novel low-dose triple single-pill combination of telmisartan, amlodipine and indapamide, compared with dual combinations for treatment of hypertension: a randomised, double-bl...

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Renal outcomes with different fixed-dose combination therapies in patients with hypertension at high risk for cardiovascular events (ACCOMPLISH): a prespecified secondary analysis of a randomised cont...

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Initial treatment with a single capsule containing half-dose quadruple therapy vs standard-dose dual therapy in hypertensive patients (QUADUAL): a randomized, blinded, crossover trial

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The Efficacy and Tolerability of Irbesartan/Amlodipine Combination Therapy in Patients With Essential Hypertension Whose Blood Pressure Were not Controlled by Irbesartan Monotherapy

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Ultra-low-dose quadruple combination blood pressure–lowering therapy in patients with hypertension: The QUARTET randomized controlled trial protocol

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Efficacy and Safety of Allisartan Isoproxil/Amlodipine in Patients With Essential Hypertension Uncontrolled by Amlodipine: A Phase III, Multicenter, Double‐Blind, Parallel‐Group, Randomized Controlled...

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Phase III randomized clinical trial of efficacy and safety of amlodipine and candesartan cilexetil combination for hypertension treatment

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Effects of body size and hypertension treatments on cardiovascular event rates: subanalysis of the ACCOMPLISH randomised controlled trial

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Randomized Polypill crossover trial in people aged 50 and over

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Efficacy of Olmesartan/Amlodipine Single‐Pill Combination on 24‐h Mean Systolic Blood Pressure Measured by Ambulatory Monitoring in Non‐Responders to Valsartan or Candesartan Monotherapy

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Pharmacokinetics and Bioequivalence of Two Fixed-Dose Combination Tablets of Valsartan/Amlodipine (80/5 Mg) in Healthy Chinese Subjects

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Efficacy and Safety of Sacubitril/Valsartan Versus Amlodipine in Japanese Patients With Essential Hypertension: A Randomized, Multicenter, Open‐Label, Noninferiority Study (PARASOL Study)

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The antihypertensive efficacy of a quadruple single-pill combination in patients with resistant hypertension: study protocol for a randomized, open-label, crossover trial

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Randomised controlled decentralised feasibility trial of a fixed low-dose combination antihypertensive drug strategy to attenuate cognitive decline in high-risk adults

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