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34 results for Amyloid+beta-Protein+Precursor+-+immunology

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ArticlesPeer ReviewedFull Text
Altered Innate Immune and Glial Cell Responses to Inflammatory Stimuli in Amyloid Precursor Protein Knockout Mice
Author / Creator:Carrano, Anna ; Das, Pritam
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-10, Vol.10 (10), p.e0140210-e0140210
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Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation
Author / Creator:Savonenko, Alena V ; Melnikova, Tatiana ; Wang, Yuchuan ; Ravert, Hayden ; Gao, Yongjun ; Koppel, Jeremy ; Lee, Deidre ; Pletnikova, Olga ; Cho, Eugenia ; Sayyida, Nuzhat ; Hiatt, Andrew ; Troncoso, Juan ; Davies, Peter ; Dannals, Robert F ; Pomper, Martin G ; Horti, Andrew G
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-06, Vol.10 (6), p.e0129618-e0129618
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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody
Author / Creator:Youmans, Katherine L ; Tai, Leon M ; Kanekiyo, Takahisa ; Stine, Jr, W Blaine ; Michon, Sara-Claude ; Nwabuisi-Heath, Evelyn ; Manelli, Arlene M ; Fu, Yifan ; Riordan, Sean ; Eimer, William A ; Binder, Lester ; Bu, Guojun ; Yu, Chunjiang ; Hartley, Dean M ; LaDu, Mary Jo
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2012-03, Vol.7 (1), p.8-8, Article 8
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Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges
Author / Creator:Cynis, Holger ; Frost, Jeffrey L ; Crehan, Helen ; Lemere, Cynthia A
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2016-06, Vol.11 (1), p.48-48, Article 48
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Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodies
Author / Creator:Höfling, Corinna ; Morawski, Markus ; Zeitschel, Ulrike ; Zanier, Elisa R. ; Moschke, Katrin ; Serdaroglu, Alperen ; Canneva, Fabio ; Hörsten, Stephan ; De Simoni, Maria‐Grazia ; Forloni, Gianluigi ; Jäger, Carsten ; Kremmer, Elisabeth ; Roßner, Steffen ; Lichtenthaler, Stefan F. ; Kuhn, Peer‐Hendrik
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2016-10, Vol.15 (5), p.953-963
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Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain
Author / Creator:Puig, Kendra L. ; Brose, Stephen A. ; Zhou, Xudong ; Sens, Mary A. ; Combs, Gerald F. ; Jensen, Michael D. ; Golovko, Mikhail Y. ; Combs, Colin K.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-03, Vol.7 (1), p.43725-43725, Article 43725
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Analyzing microglial-associated Aβ in Alzheimer’s disease transgenic mice with a novel mid-domain Aβ-antibody
Author / Creator:Henjum, Kristi ; Årskog, Vibeke ; Jendresen, Charlotte B. ; Fladby, Tormod ; Torp, Reidun ; Nilsson, Lars N. G.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-06, Vol.10 (1), p.10590-10590, Article 10590
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Prominent Neurodegeneration and Increased Plaque Formation in Complement-Inhibited Alzheimer's Mice
Author / Creator:Wyss-Coray, Tony ; Yan, Fengrong ; Lin, Amy Hsiu-Ti ; Lambris, John D. ; Alexander, Jessy J. ; Quigg, Richard J. ; Masliah, Eliezer
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10837-10842
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Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice
Author / Creator:Brendza, Robert P ; Bacskai, Brian J ; Cirrito, John R ; Simmons, Kelly A ; Skoch, Jesse M ; Klunk, William E ; Mathis, Chester A ; Bales, Kelly R ; Paul, Steven M ; Hyman, Bradley T ; Holtzman, David M
Publisher:United States
Journal title:The Journal of clinical investigation, 2005-02, Vol.115 (2), p.428-433
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Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transgenic rats: rapid rev...
Author / Creator:Qi, Yingjie ; Klyubin, Igor ; Harney, Sarah C ; Hu, NengWei ; Cullen, William K ; Grant, Marianne K ; Steffen, Julia ; Wilson, Edward N ; Do Carmo, Sonia ; Remy, Stefan ; Fuhrmann, Martin ; Ashe, Karen H ; Cuello, A Claudio ; Rowan, Michael J
Publisher:England: BioMed Central Ltd
Journal title:Acta neuropathologica communications, 2014-12, Vol.2 (1), p.175-175, Article 175
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Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease
Author / Creator:Sudol, Kelly L ; Mastrangelo, Michael A ; Narrow, Wade C ; Frazer, Maria E ; Levites, Yona R ; Golde, Todd E ; Federoff, Howard J ; Bowers, William J
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2009-12, Vol.17 (12), p.2031-2040
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A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer’s Disease
Author / Creator:Vigo, Carmen ; Lakshmana, Madepalli Krishnappa ; Lombardi, Valter R. M. ; Fernández-Novoa, Lucía ; Etcheverría, Ignacio ; Carrera, Iván ; Cacabelos, Ramón
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2015-01, Vol.2015 (2015), p.1-16
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ArticlesPeer ReviewedFull Text
Inhibition of Amyloid Precursor Protein Processing by β-Secretase through Site-Directed Antibodies
Author / Creator:Arbel, Michal ; Yacoby, Iftach ; Solomon, Beka ; Katchalski-Katzir, Ephraim
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2005-05, Vol.102 (21), p.7718-7723
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Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine
Author / Creator:Aliev, Gjumrakch ; Cacabelos, Ramón ; Palacios, Hector H. ; Vigo, Carmen ; Lombardi, Valter ; Fernández-Novoa, Lucía ; Li, Yi ; Etcheverría, Ignacio ; Carrera, Iván ; Benberin, Valery V.
Publisher:Cairo, Egypt: Hindawi Publishing Corporation
Journal title:BioMed research international, 2013-01, Vol.2013 (2013), p.1-12
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Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice
Author / Creator:Rabinovich-Nikitin, Inna ; Rakover, Idan S ; Becker, Maria ; Solomon, Beka
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-10, Vol.7 (10), p.e46650
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ArticlesPeer ReviewedFull Text
Specific antibody binding to the APP672–699 region shifts APP processing from α- to β-cleavage
Author / Creator:Li, S ; Deng, J ; Hou, H ; Tian, J ; Giunta, B ; Wang, Y ; Sawmiller, D ; Smith, A ; Sanberg, P R ; Obregon, D ; Mori, T ; Tan, J
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2014-08, Vol.5 (8), p.e1374-e1374
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APLP1 as a cerebrospinal fluid biomarker for γ-secretase modulator treatment
Author / Creator:Sjödin, Simon ; Andersson, Kerstin K A ; Mercken, Marc ; Zetterberg, Henrik ; Borghys, Herman ; Blennow, Kaj ; Portelius, Erik
Publisher:England: BioMed Central
Journal title:Alzheimer's research & therapy, 2015-12, Vol.7 (1), p.77-77, Article 77
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ArticlesPeer ReviewedFull Text
Amyloid Precursor Protein Expression Modulates Intestine Immune Phenotype
Author / Creator:Puig, Kendra L. ; Swigost, Adam J. ; Zhou, Xudong ; Sens, Mary Ann ; Combs, Colin K.
Publisher:Boston: Springer US
Journal title:Journal of neuroimmune pharmacology, 2012-03, Vol.7 (1), p.215-230
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ArticlesPeer ReviewedFull Text
Staining of amyloid precursor protein to study axonal damage in mild head injury
Author / Creator:BLUMBERGS, P. C ; SCOTT, G ; MANAVIS, J ; WAINWRIGHT, H ; SIMPSON, D. A ; MCLEAN, A. J
Publisher:London: Lancet
Journal title:The Lancet (British edition), 1994-10, Vol.344 (8929), p.1055-1056
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Heavy-Chain Complementarity-Determining Regions Determine Conformation Selectivity of Anti-Aβ Antibodies
Author / Creator:Sehlin, Dag ; Hedlund, Marie ; Lord, Anna ; Englund, Hillevi ; Gellerfors, Pär ; Paulie, Staffan ; Lannfelt, Lars ; Pettersson, Frida Ekholm
Publisher:Basel, Switzerland
Journal title:Neuro-degenerative diseases, 2011-01, Vol.8 (3), p.117-123
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Showing 1 to 20 of 34 results

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Altered Innate Immune and Glial Cell Responses to Inflammatory Stimuli in Amyloid Precursor Protein Knockout Mice

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Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation

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Intraneuronal Aβ detection in 5xFAD mice by a new Aβ-specific antibody

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Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges

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Differential transgene expression patterns in Alzheimer mouse models revealed by novel human amyloid precursor protein‐specific antibodies

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Amyloid precursor protein modulates macrophage phenotype and diet-dependent weight gain

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Analyzing microglial-associated Aβ in Alzheimer’s disease transgenic mice with a novel mid-domain Aβ-antibody

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Prominent Neurodegeneration and Increased Plaque Formation in Complement-Inhibited Alzheimer's Mice

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Anti-Abeta antibody treatment promotes the rapid recovery of amyloid-associated neuritic dystrophy in PDAPP transgenic mice

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Longitudinal testing of hippocampal plasticity reveals the onset and maintenance of endogenous human Aß-induced synaptic dysfunction in individual freely behaving pre-plaque transgenic rats: rapid rev...

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Generating Differentially Targeted Amyloid-β Specific Intrabodies as a Passive Vaccination Strategy for Alzheimer's Disease

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A Comparative Evaluation of a Novel Vaccine in APP/PS1 Mouse Models of Alzheimer’s Disease

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Inhibition of Amyloid Precursor Protein Processing by β-Secretase through Site-Directed Antibodies

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Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

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Beneficial effect of antibodies against β- secretase cleavage site of APP on Alzheimer's-like pathology in triple-transgenic mice

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Specific antibody binding to the APP672–699 region shifts APP processing from α- to β-cleavage

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APLP1 as a cerebrospinal fluid biomarker for γ-secretase modulator treatment

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Amyloid Precursor Protein Expression Modulates Intestine Immune Phenotype

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Staining of amyloid precursor protein to study axonal damage in mild head injury

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Heavy-Chain Complementarity-Determining Regions Determine Conformation Selectivity of Anti-Aβ Antibodies

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