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782 results for Antineoplastic+Combined+Chemotherapy+Protocols+-+pharmacokinetics

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Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...
Author / Creator:Tabernero, Josep ; Hoff, Paulo M ; Shen, Lin ; Ohtsu, Atsushi ; Shah, Manish A ; Cheng, Karen ; Song, Chunyan ; Wu, Haiyan ; Eng-Wong, Jennifer ; Kim, Katherine ; Kang, Yoon-Koo
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-10, Vol.19 (10), p.1372-1384
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A nanotherapeutic strategy to overcome chemotherapeutic resistance of cancer stem-like cells
Author / Creator:Shen, Shiyang ; Xu, Xiao ; Lin, Shiqi ; Zhang, Ying ; Liu, Huayu ; Zhang, Can ; Mo, Ran
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2021-01, Vol.16 (1), p.104-113
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Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer
Author / Creator:Melisi, Davide ; Garcia-Carbonero, Rocio ; Macarulla, Teresa ; Pezet, Denis ; Deplanque, Gael ; Fuchs, Martin ; Trojan, Jorg ; Oettle, Helmut ; Kozloff, Mark ; Cleverly, Ann ; Smith, Claire ; Estrem, Shawn T. ; Gueorguieva, Ivelina ; Lahn, Michael M. F. ; Blunt, Al ; Benhadji, Karim A. ; Tabernero, Josep
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2018-11, Vol.119 (10), p.1208-1214
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A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients
Author / Creator:Kanai, Masashi ; Otsuka, Yoshihiko ; Otsuka, Kazunori ; Sato, Maremi ; Nishimura, Takafumi ; Mori, Yukiko ; Kawaguchi, Michiya ; Hatano, Etsuro ; Kodama, Yuzo ; Matsumoto, Shigemi ; Murakami, Yoshiki ; Imaizumi, Atsushi ; Chiba, Tsutomu ; Nishihira, Jun ; Shibata, Hiroyuki
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer chemotherapy and pharmacology, 2013-06, Vol.71 (6), p.1521-1530
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Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations
Author / Creator:Flaherty, Keith T ; Infante, Jeffery R ; Daud, Adil ; Gonzalez, Rene ; Kefford, Richard F ; Sosman, Jeffrey ; Hamid, Omid ; Schuchter, Lynn ; Cebon, Jonathan ; Ibrahim, Nageatte ; Kudchadkar, Ragini ; Burris, Howard A ; Falchook, Gerald ; Algazi, Alain ; Lewis, Karl ; Long, Georgina V ; Puzanov, Igor ; Lebowitz, Peter ; Singh, Ajay ; Little, Shonda ; Sun, Peng ; Allred, Alicia ; Ouellet, Daniele ; Kim, Kevin B ; Patel, Kiran ; Weber, Jeffrey
Publisher:Waltham, MA: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2012-11, Vol.367 (18), p.1694-1703
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Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours
Author / Creator:Middleton, Mark R. ; Dean, Emma ; Evans, Thomas R. J. ; Shapiro, Geoffrey I. ; Pollard, John ; Hendriks, Bart S. ; Falk, Martin ; Diaz-Padilla, Ivan ; Plummer, Ruth
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2021-08, Vol.125 (4), p.510-519
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Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiorit...
Author / Creator:Tan, Antoinette R, Prof ; Im, Seock-Ah, Prof ; Mattar, André, Prof ; Colomer, Ramon, Prof ; Stroyakovskii, Daniil, Prof ; Nowecki, Zbigniew, Prof ; De Laurentiis, Michelino, Prof ; Pierga, Jean-Yves, Prof ; Jung, Kyung Hae, Prof ; Schem, Christian, Prof ; Hogea, Alexandra, PhD ; Badovinac Crnjevic, Tanja, MD ; Heeson, Sarah, BSc ; Shivhare, Mahesh, PhD ; Kirschbrown, Whitney P, PhD ; Restuccia, Eleonora, MD ; Jackisch, Christian, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-01, Vol.22 (1), p.85-97
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Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption
Author / Creator:Arvanitis, Costas D. ; Askoxylakis, Vasileios ; Guo, Yutong ; Datta, Meenal ; Kloepper, Jonas ; Ferraro, Gino B. ; Bernabeu, Miguel O. ; Fukumura, Dai ; McDannold, Nathan ; Jain, Rakesh K.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-09, Vol.115 (37), p.E8717-E8726
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ArticlesPeer ReviewedFull Text
Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma
Author / Creator:Miklja, Zachary ; Yadav, Viveka Nand ; Cartaxo, Rodrigo T. ; Siada, Ruby ; Thomas, Chase C. ; Cummings, Jessica R. ; Mullan, Brendan ; Stallard, Stefanie ; Paul, Alyssa ; Bruzek, Amy K. ; Wierzbicki, Kyle ; Yang, Tao ; Garcia, Taylor ; Wolfe, Ian ; Leonard, Marcia ; Robertson, Patricia L. ; Garton, Hugh J.L. ; Wahl, Daniel R. ; Parmar, Hemant ; Sarkaria, Jann N. ; Kline, Cassie ; Mueller, Sabine ; Nicolaides, Theodore ; Glasser, Chana ; Leary, Sarah E.S. ; Venneti, Sriram ; Kumar-Sinha, Chandan ; Chinnaiyan, Arul M. ; Mody, Rajen ; Pai, Manjunath P. ; Phoenix, Timothy N. ; Marini, Bernard L. ; Koschmann, Carl
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2020-10, Vol.130 (10), p.5313-5325
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Panobinostat: First Global Approval
Author / Creator:Garnock-Jones, Karly P.
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2015-04, Vol.75 (6), p.695-704
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Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs
Author / Creator:Sugahara, Kazuki N. ; Teesalu, Tambet ; Karmali, Priya Prakash ; Kotamraju, Venkata Ramana ; Agemy, Lilach ; Greenwald, Daniel R. ; Ruoslahti, Erkki
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-05, Vol.328 (5981), p.1031-1035
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Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy
Author / Creator:Leijen, Suzanne ; Burgers, Sjaak A. ; Baas, Paul ; Pluim, Dick ; Tibben, Matthijs ; van Werkhoven, Erik ; Alessio, Enzo ; Sava, Gianni ; Beijnen, Jos H. ; Schellens, Jan H. M.
Publisher:Boston: Springer US
Journal title:Investigational new drugs, 2015-02, Vol.33 (1), p.201-214
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Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect
Author / Creator:Bocci, Guido ; Kerbel, Robert S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2016-11, Vol.13 (11), p.659-673
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A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer
Author / Creator:Schweizer, Michael T. ; Haugk, Kathleen ; McKiernan, Jožefa S. ; Gulati, Roman ; Cheng, Heather H. ; Maes, Jessica L. ; Dumpit, Ruth F. ; Nelson, Peter S. ; Montgomery, Bruce ; McCune, Jeannine S. ; Plymate, Stephen R. ; Yu, Evan Y.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-06, Vol.13 (6), p.e0198389
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A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma
Author / Creator:Cook, Natalie ; Basu, Bristi ; Smith, Donna-Michelle ; Gopinathan, Aarthi ; Evans, Jeffry ; Steward, William P ; Palmer, Daniel ; Propper, David ; Venugopal, Balaji ; Hategan, Mirela ; Anthoney, D Alan ; Hampson, Lisa V ; Nebozhyn, Michael ; Tuveson, David ; Farmer-Hall, Hayley ; Turner, Helen ; McLeod, Robert ; Halford, Sarah ; Jodrell, Duncan
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2018-03, Vol.118 (6), p.793-801
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Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours
Author / Creator:Di Mascolo, Daniele ; Palange, Anna Lisa ; Primavera, Rosita ; Macchi, Francesca ; Catelani, Tiziano ; Piccardi, Federica ; Spanò, Raffaele ; Ferreira, Miguel ; Marotta, Roberto ; Armirotti, Andrea ; Gallotti, Alberto L. ; Galli, Rossella ; Wilson, Christy ; Grant, Gerald A. ; Decuzzi, Paolo
Publisher:London: Nature Publishing Group UK
Journal title:Nature nanotechnology, 2021-07, Vol.16 (7), p.820-829
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High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study
Author / Creator:Polireddy, Kishore ; Dong, Ruochen ; Reed, Gregory ; Yu, Jun ; Chen, Ping ; Williamson, Stephen ; Violet, Pierre-Christian ; Pessetto, Ziyan ; Godwin, Andrew K. ; Fan, Fang ; Levine, Mark ; Drisko, Jeanne A. ; Chen, Qi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-12, Vol.7 (1), p.17188-15, Article 17188
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Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines
Author / Creator:Jamshidifar, Elham ; Eshrati Yeganeh, Faten ; Shayan, Mona ; Tavakkoli Yaraki, Mohammad ; Bourbour, Mahsa ; Moammeri, Ali ; Akbarzadeh, Iman ; Noorbazargan, Hassan ; Hossein-Khannazer, Nikoo
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2021-07, Vol.22 (15), p.7948
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Ixazomib: First Global Approval
Author / Creator:Shirley, Matt
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2016-03, Vol.76 (3), p.405-411
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Phase I/II study of nab-paclitaxel plus gemcitabine for chemotherapy-naive Japanese patients with metastatic pancreatic cancer
Author / Creator:Ueno, Hideki ; Ikeda, Masafumi ; Ueno, Makoto ; Mizuno, Nobumasa ; Ioka, Tatsuya ; Omuro, Yasushi ; Nakajima, Takako Eguchi ; Furuse, Junji
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer chemotherapy and pharmacology, 2016-03, Vol.77 (3), p.595-603
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Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...

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A nanotherapeutic strategy to overcome chemotherapeutic resistance of cancer stem-like cells

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Galunisertib plus gemcitabine vs. gemcitabine for first-line treatment of patients with unresectable pancreatic cancer

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A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin®) in cancer patients

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Combined BRAF and MEK Inhibition in Melanoma with BRAF V600 Mutations

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Phase 1 study of the ATR inhibitor berzosertib (formerly M6620, VX-970) combined with gemcitabine ± cisplatin in patients with advanced solid tumours

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Fixed-dose combination of pertuzumab and trastuzumab for subcutaneous injection plus chemotherapy in HER2-positive early breast cancer (FeDeriCa): a randomised, open-label, multicentre, non-inferiorit...

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Mechanisms of enhanced drug delivery in brain metastases with focused ultrasound-induced blood–tumor barrier disruption

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Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma

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Panobinostat: First Global Approval

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Coadministration of a Tumor-Penetrating Peptide Enhances the Efficacy of Cancer Drugs

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Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy

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Pharmacokinetics of metronomic chemotherapy: a neglected but crucial aspect

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A phase I study of niclosamide in combination with enzalutamide in men with castration-resistant prostate cancer

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A phase I trial of the γ-secretase inhibitor MK-0752 in combination with gemcitabine in patients with pancreatic ductal adenocarcinoma

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Conformable hierarchically engineered polymeric micromeshes enabling combinatorial therapies in brain tumours

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High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study

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Super Magnetic Niosomal Nanocarrier as a New Approach for Treatment of Breast Cancer: A Case Study on SK-BR-3 and MDA-MB-231 Cell Lines

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Ixazomib: First Global Approval

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Phase I/II study of nab-paclitaxel plus gemcitabine for chemotherapy-naive Japanese patients with metastatic pancreatic cancer

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